2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 代谢化合物库系列
  6. 人代谢物库
人代谢物库 - Human Metabolite Library

Cat. No.: HY-L123

人体新陈代谢是细胞功能的一个组成部分，可以反映健康、疾病、饮食和生活方式的个体差异。许多健康状况，如肥胖、糖尿病、高血压、心脏病和癌症都与异常代谢状态有关。在人体处于病理状态时，代谢途径显著改变，导致中间体或终产物水平异常，这些中间体或终产物可被视为潜在的诊断生物标志物甚至治疗靶点。因此，人体代谢产物的检测、鉴定和定量对药物开发中药物代谢研究十分重要。

MCE提供6,190人代谢物，包括内源性代谢物及外源性代谢物。涉及脂类、氨基酸、核酸、碳水化合物、有机酸、生物胺、维生素等多种结构。MCE人代谢物库是研究疾病与代谢组之间关系的有效工具。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 人代谢物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，6,045 个产品以 10 mM 浓度提供，126 个产品以 2 mM 浓度提供，19 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 6,190 human metabolites for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for studying the relationship between diseases and metabolism.

•   Target diverse, medicinally active and cell permeable.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

产品详情

Product Details

Formulation:

A collection of 6,190 human metabolites supplied as pre-dissolved Solutions or Solid
Solution: 6,045 compounds supplied in 10 mM solution, 126 compounds supplied in 2 mM solution, 19 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice

化合物库组成

Composition

Fungal (184)

COX (164)

NF-κB (140)

HIV (111)

iGluR (60)

PPAR (59)

mAChR (57)

PI3K (52)

VEGFR (50)

Akt (48)

EGFR (43)

MMP (41)

ERK (38)

HSV (38)

PDGFR (36)

STAT (34)

PKC (30)

CDK (28)

HCV (28)

mTOR (27)

nAChR (27)

AMPK (26)

c-Kit (26)

HBV (26)

PARP (26)

FGFR (24)

HDAC (23)

JAK (21)

mGluR (21)

FLT3 (20)

Src (19)

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  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
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联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Human Metabolite Library
    目录号：
    HY-L123
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