2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 代谢化合物库系列
  6. 微生物代谢物库
微生物代谢物库 - Microbial Metabolite Library

Cat. No.: HY-L084

几千年来，大自然一直是药物的重要来源，但许多有用的活性物质都是从植物中开发出来。20 世纪，青霉素的发现是从微生物中进行药物开发的起点。微生物作为生物活性化合物的丰富来源，在天然产物开发和疾病治疗中发挥着重要作用。微生物代谢物作为有效的抗菌药物、抗肿瘤药物、酶抑制剂、抗炎药物等已经被广泛应用于临床治疗。如今，许多来源于微生物的抗生素都已问世，大量具有生物活性的代谢物也被用于医学研究。

MCE可以提供 1,121 种具有明确的微生物代谢物，是先导化合物的重要来源，可以用于药物开发。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 微生物代谢物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，1,073 个产品以 10 mM 浓度提供，32 个产品以 2 mM 浓度提供，16 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 1,121 microbial metabolites for high throughput screening (HTS) and high content screening (HCS).

•   All compounds derived from microbes with better bioavailability.

•   A useful tool for microbial metabolites-related drug discovery.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 1,121 microbial metabolite related compounds supplied as pre-dissolved Solutions or Solid
Solution: 1,073 compounds supplied in 10 mM solution, 32 compounds supplied in 2 mM solution, 16 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

COX (15)

HSV (12)

iGluR (11)

HIV (10)

MMP (8)

PI3K (8)

Akt (6)

PKC (6)

PPAR (6)

mTOR (5)

STAT (5)

EGFR (4)

PARP (4)

AMPK (3)

ERK (3)

FKBP (3)

HBV (3)

JNK (3)

Wnt (3)

BCL6 (2)

CXCR (2)

FGFR (2)

FXR (2)

HCV (2)

HDAC (2)

HSP (2)

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定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Microbial Metabolite Library
    目录号：
    HY-L084
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