2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 代谢化合物库系列
  6. 肠道菌群代谢化合物库
肠道菌群代谢化合物库 - Gut Microbial Metabolite Library

Cat. No.: HY-L078

越来越多的研究表明，肠道菌群在人类健康及疾病发展方面发挥越来越重要的作用。肠道菌群失调与多种疾病的发生发展有关，如心血管疾病、炎症性肠道疾病、糖尿病、高血压、癌症及抑郁症等。事实上，肠道微生物的功能就像人体的一种内分泌器官，产生生物活性代谢物，这些代谢物在人类新陈代谢、健康和疾病中发挥重要作用。肠道微生物目前也成为一种新的潜在治疗靶点，有望用于多种疾病的治疗，而对肠道微生物代谢物的分析和鉴定，将有助于新的治疗方法的开发。

为了满足对肠道微生物的研究需求，MCE 精心挑选了 510 个肠道微生物代谢物。MCE肠道微生物代谢物库将有助于肠道微生物研究及相关药物开发。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 肠道菌群代谢化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，496 个产品以 10 mM 浓度提供，9 个产品以 2 mM 浓度提供，5 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 510 gut microbial metabolites for high throughput screening (HTS) and high content screening (HCS).

•   The compounds derived from gut microbiome with better bioavailability.

•   A useful tool for gut microbiome research and gut microbiome -related drug discovery.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 510 gut microbial metabolites supplied as pre-dissolved Solutions or Solid
Solution: 496 compounds supplied in 10 mM solution, 9 compounds supplied in 2 mM solution, 5 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

COX (7)

PI3K (4)

PPAR (4)

STAT (4)

HIV (3)

HSV (3)

BCL6 (2)

CXCR (2)

EGFR (2)

FGFR (2)

FXR (2)

HBV (2)

MMP (2)

AMPK (1)

CFTR (1)

ERK (1)

GLUT (1)

GlyT (1)

JAK (1)

JNK (1)

mTOR (1)

PARP (1)

PKA (1)

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  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Gut Microbial Metabolite Library
    目录号：
    HY-L078
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