1. 一站式药筛
  2. 化合物库
  3. 氨基酸代谢库
氨基酸代谢库 - Amino Acid Metabolism Compound Library

Cat. No.: HY-L189

氨基酸作为生物体内最基本的有机化合物之一,不仅是蛋白质的基本组成单位,还承担着能量供给、神经递质合成、维持内环境稳定等功能。氨基酸代谢酶是一类参与氨基酸代谢过程的酶,负责催化氨基酸的合成、分解、转化以及与其他代谢途径的交互。氨基酸代谢酶的异常可能导致多种代谢性疾病,如苯丙酮尿症 (Phenylketonuria) 和高氨血症 (Hyperammonemia) 等疾病。因此,积极探究和调控氨基酸代谢过程对于代谢类相关疾病的药物开发至关重要。

MCE 收录了 227 个靶向氨基酸代谢酶的小分子化合物,是研究氨基酸代谢过程或进行代谢相关药物开发的重要工具。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE 氨基酸代谢库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,222 个产品以 10 mM 浓度提供,5 个产品以 2 mM 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

Top Publications Citing Use of MCE Products

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 227 amino acid metabolizing enzymes related compounds for high throughput screening (HTS) and high content screening (HCS).

•   The compound library targets include arginase, Dipeptidyl Peptidase, Glutaminase,etc.

•   A useful tool for the discovery of compounds for metabolism-related dieases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 227 compounds related of amino acid metabolism supplied as pre-dissolved Solutions or Solid.
Solution: 222 compounds supplied in 10 mM solution, 5 compounds supplied in 2 mM solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

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  •  形式(固体或溶液)
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  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    Amino Acid Metabolism Compound Library
    目录号:
    HY-L189
    需求量: