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  5. 20-Deoxyingenol 3-angelate

20-Deoxyingenol 3-angelate (DI3A) 增加 NK 细胞的脱颗粒和干扰素-γ 分泌。20-Deoxyingenol 3-angelate 增强 NK 细胞杀肿瘤活性。

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20-Deoxyingenol 3-angelate Chemical Structure

20-Deoxyingenol 3-angelate Chemical Structure

CAS No. : 75567-38-3

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规格 价格 是否有货 数量
1 mg ¥4600
1 - 2 周
5 mg 现货 1 - 2 周
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

20-Deoxyingenol 3-angelate (DI3A) increases degranulation and interferon-gamma secretion of NK cells. 20-Deoxyingenol 3-angelate enhances NK cell tumoricidal activity[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HeLa IC50
> 10 μM
Compound: 12
Cytotoxicity against human HeLa cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
HepG2 IC50
> 10 μM
Compound: 12
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
MT4 CC50
> 9.7 μM
Compound: 17
Cytotoxicity against human MT4 cells after 3 days by CytoTox-Glo assay
Cytotoxicity against human MT4 cells after 3 days by CytoTox-Glo assay
[PMID: 30031972]
PC-3 IC50
> 10 μM
Compound: 12
Cytotoxicity against human PC-3 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
SK-MEL-28 IC50
> 10 μM
Compound: 12
Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
分子量

414.53

Formula

C25H34O5

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
20-Deoxyingenol 3-angelate
目录号:
HY-N1684
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