1. 天然产物
  2. 植物 萜类
  3. 七叶树科 三萜
  4. 七叶树
  5. 21-Angeloyl-protoaescigenin

21-Angeloyl-protoaescigenin  (Synonyms: (Z)-Protoescigenin 21-tiglate)

目录号: HY-N13115
产品使用指南

21-Angeloyl-protoaescigenin (compound 11) 是一种糖苷类七叶树籽样三萜 (BAT),能够从七叶树籽粗提取物的酸水解产物 (AHP) 中分离得到。七叶树籽样三萜 (BAT) 通常具有良好的抗肿瘤、抗炎和抗阿尔茨海默病活性。但 Protoescigenin 21-tiglate 具有抗肿瘤活性,对 MCF-7 和 HeLa 的抑制效力 (IC50) 分别为 38.2 μM 和 33 μM。

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21-Angeloyl-protoaescigenin Chemical Structure

21-Angeloyl-protoaescigenin Chemical Structure

CAS No. : 35931-54-5

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Other Forms of 21-Angeloyl-protoaescigenin:

  • 生物活性

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  • 参考文献

生物活性

21-Angeloyl-protoaescigenin (compound 11) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. Protoescigenin 21-tiglate has antitumor activity, with IC50 values of 38.2 μM and 33 μM against MCF-7 and HeLa cells, respectively[1].

分子量

588.81

Formula

C35H56O7

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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