2. MAPK/ERK Pathway Metabolic Enzyme/Protease
  3. MAP3K MAP4K Phosphatase
  4. 3,4-Dephostatin

3,4-Dephostatin  (Synonyms: Methyl-3,4-dephostatin)

目录号: HY-124152
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摩尔计算器

3,4-Dephostatin (Methyl-3,4-dephostatin) 是一种蛋白酪氨酸磷酸酶 (PTPase) 抑制剂。3,4-Dephostatin 加速神经生长因子 (NGF) 诱导的 PC12h 细胞神经突起形成。3,4-Dephostatin 维持 NGF 诱导的蛋白质酪氨酸磷酸化，尤其是有丝分裂原激活蛋白 (MAP) 激酶的磷酸化。3,4-Dephostatin 还延长表皮生长因子 (EGF) 诱导的酪氨酸磷酸化和 MAP 激酶的激活。

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3,4-Dephostatin Chemical Structure

3,4-Dephostatin Chemical Structure

CAS No. : 173043-84-0

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3,4-Dephostatin 相关抗体

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生物活性

3,4-Dephostatin (Methyl-3,4-dephostatin) is an inhibitor of protein-tyrosine phosphatase (PTPase). 3,4-Dephostatin accelerates nerve growth factor (NGF)-induced neurite formation in PC12h cells. 3,4-Dephostatin sustains the NGF-induced tyrosine phosphorylation of proteins, most prominently that of mitogen-activated protein (MAP) kinase. 3,4-Dephostatin also prolongs epidermal growth factor (EGF)-induced tyrosine phosphorylation and activation of MAP kinase[1].

分子量

168.15

Formula

C7H8N2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3,4-Dephostatin 相关分类

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Keywords:

3,4-Dephostatin173043-84-0Methyl-3,4-dephostatinMAP3KMAP4KPhosphataseMAP kinase kinase kinase, MEKK, MAPKKKMAPK Kinase Kinase KinasePTPaseNGFneurite formationPC12h cellstyrosine phosphorylationMAPEGFInhibitorinhibitorinhibit

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