2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 3'-Deoxy-3'-fluoroadenosine

3'-Deoxy-3'-fluoroadenosine 

目录号: HY-102018 纯度: 99.29%
COA 产品使用指南

摩尔计算器

3'-Deoxy-3'-fluoroadenosine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。

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3'-Deoxy-3'-fluoroadenosine Chemical Structure

3'-Deoxy-3'-fluoroadenosine Chemical Structure

CAS No. : 75059-22-2

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规格 价格 是否有货 数量
5 mg ￥400
In-stock
10 mg ￥650
In-stock
25 mg ￥1310
In-stock
50 mg ￥2100
In-stock
100 mg ￥3350
In-stock
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500 mg   询价  

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3'-Deoxy-3'-fluoroadenosine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MRC5 EC50
4.92 μM
Compound: 6
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 3 days by resazurin dye based fluorimetric analysis
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 3 days by resazurin dye based fluorimetric analysis
[PMID: 33667845]
分子量

269.24

Formula

C10H12FN5O3
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: 99.29%

COA (291 KB) HNMR (141 KB) LCMS (92 KB)

产品使用指南 (1538 KB)
参考文献

3'-Deoxy-3'-fluoroadenosine 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3'-Deoxy-3'-fluoroadenosine75059-22-2Nucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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