2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 疾病相关化合物库
  6. 抗血液病化合物库
抗血液病化合物库 - Anti-Hematopathy Compound Library

Cat. No.: HY-L171

血液病又称造血系统疾病，是造血系统发生异常改变的一类疾病。常见的血液病包括：再生障碍性贫血、骨髓增生性疾病、地中海贫血、白血病、淋巴瘤、骨髓瘤以及血友病等。近些年，血液病的治疗方法一直在不断开发。尤其是恶性血液病的治疗手段已从既往的化疗、放疗和骨髓移植治疗进展到免疫治疗、诱导分化治疗、细胞治疗、基因治疗和造血干细胞移植治疗等。尽管这些治疗手段已经大大提高了患者的生存率，但仍存在治愈率低、易复发等问题，因此积极寻找新的血液病治疗药物具有重要意义。

MCE 精心收录了 2,930 种具有明确或潜在抗血液病活性的化合物，是血液病相关药物研究的有效工具。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 抗血液病化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，2,868 个产品以 10 mM 浓度提供，57 个产品以 2 mM 浓度提供，5 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 2,930 anti-hematopathy compounds for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of anti-hematopathy diseases compounds such as aplastic anemia, mediterranean anemia, leukemia, haemophilia, etc.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 2,930 bioactive compounds related to hematopathy supplied as pre-dissolved Solutions or Solid.
Solution: 2,868 compounds supplied in 10 mM solution, 57 compounds supplied in 2 mM solution, 5 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

CDK (254)

NF-κB (242)

PI3K (184)

VEGFR (155)

HDAC (135)

JAK (123)

Akt (110)

STAT (103)

mTOR (97)

Ras (94)

FLT3 (84)

PDGFR (69)

c-Kit (61)

Btk (59)

HIV (41)

FGFR (39)

EGFR (37)

Src (33)

COX (29)

GSK-3 (26)

ERK (23)

AMPK (19)

HSV (18)

JNK (16)

c-Fms (14)

PKC (14)

Raf (13)

RET (13)

MMP (12)

Syk (12)

HSP (11)

PARP (10)

FAK (9)

IRAK (9)

DYRK (8)

IKK (8)

相关服务推荐
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  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
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联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Anti-Hematopathy Compound Library
    目录号：
    HY-L171
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