2. 天然产物
  3. 植物 黄酮类
  4. 三尖杉科 查耳酮
  5. 粗榧
  6. 4-O-Methylhelichrysetin

4-O-Methylhelichrysetin  (Synonyms: 2',4'-二羟基-4,6'-二甲氧基查耳酮)

目录号: HY-N1911
产品使用指南 技术支持

4-O-Methylhelichrysetin 是一种查尔酮，可以从三尖杉属植物中分离得到。

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4-O-Methylhelichrysetin Chemical Structure

4-O-Methylhelichrysetin Chemical Structure

CAS No. : 56121-44-9

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4-O-Methylhelichrysetin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

4-O-Methylhelichrysetin is a Chalcones product that can be isolated from the herbs of Cephalotaxus sinensis[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 50 μM
Compound: 11b
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
[PMID: 25629304]
DU-145 GI50
9 μM
Compound: 6
Cytotoxicity against human DU145 cells after 48 hrs
Cytotoxicity against human DU145 cells after 48 hrs
[PMID: 18798609]
HeLa IC50
47.7 μM
Compound: 11b
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
[PMID: 25629304]
HepG2 IC50
18.1 μM
Compound: 11b
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
[PMID: 25629304]
HT-29 GI50
21.6 μM
Compound: 6
Cytotoxicity against human HT29 cells after 48 hrs
Cytotoxicity against human HT29 cells after 48 hrs
[PMID: 18798609]
K562 GI50
17 μM
Compound: 6
Cytotoxicity against human K562 cells after 48 hrs
Cytotoxicity against human K562 cells after 48 hrs
[PMID: 18798609]
M14 GI50
19.6 μM
Compound: 6
Cytotoxicity against human M14 cells after 48 hrs
Cytotoxicity against human M14 cells after 48 hrs
[PMID: 18798609]
Macrophage IC50
166.2 μM
Compound: 26
Toxicity against BALB/c mouse macrophage by MTT assay
Toxicity against BALB/c mouse macrophage by MTT assay
[PMID: 19962891]
MCF7 GI50
17.3 μM
Compound: 6
Cytotoxicity against human MCF7 cells after 48 hrs
Cytotoxicity against human MCF7 cells after 48 hrs
[PMID: 18798609]
NCI-H460 GI50
14 μM
Compound: 6
Cytotoxicity against human H460 cells after 48 hrs
Cytotoxicity against human H460 cells after 48 hrs
[PMID: 18798609]
NIH3T3 GI50
6.7 μM
Compound: 6
Cytotoxicity against BALB mouse 3T3 cells after 48 hrs
Cytotoxicity against BALB mouse 3T3 cells after 48 hrs
[PMID: 18798609]
PC-3 GI50
19.3 μM
Compound: 6
Cytotoxicity against human PC3 cells after 48 hrs
Cytotoxicity against human PC3 cells after 48 hrs
[PMID: 18798609]
Vero IC50
> 25 μM
Compound: 6
Antitrypanosomal activity against Trypanosoma cruzi Tulahuen C4 in african green monkey Vero cells after 120 hrs
Antitrypanosomal activity against Trypanosoma cruzi Tulahuen C4 in african green monkey Vero cells after 120 hrs
[PMID: 18798609]
分子量

300.31

Formula

C17H16O5
CAS 号
中文名称

2',4'-二羟基-4,6'-二甲氧基查耳酮
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

4-O-Methylhelichrysetin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-O-Methylhelichrysetin56121-44-92',4'-二羟基-4,6'-二甲氧基查耳酮OthersInhibitorinhibitorinhibit

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