2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. 5-HT2A/5-HT2C inverse agonist 1

5-HT2A/5-HT2C inverse agonist 1 

目录号: HY-169001
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5-HT2A/5-HT2C inverse agonist 1 是一种强效的 5-HT2A 和 5-HT2C 受体双重反激动剂，具有 hERG 抑制作用，从而避免心血管风险。5-HT2A/5-HT2C inverse agonist 1 在 MK-801 (HY-15084B) 诱导的小鼠模型中显示出显著的抗精神病疗效。5-HT2A/5-HT2C inverse agonist 1 有望用于精神病的研究。

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5-HT2A/5-HT2C inverse agonist 1 Chemical Structure

5-HT2A/5-HT2C inverse agonist 1 Chemical Structure

CAS No. : 2718990-76-0

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5-HT2A/5-HT2C inverse agonist 1 相关抗体

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生物活性

5-HT2A/5-HT2C inverse agonist 1 is a potent and dual 5-HT2A and 5-HT2C receptor inverse agonist with a hERG inhibitions, thus avoiding cardiovascular risks. 5-HT2A/5-HT2C inverse agonist 1 shows significant antipsychotic efficacy in the MK-801 (HY-15084B)-induced mouse model. 5-HT2A/5-HT2C inverse agonist 1 is promising for research of psychosis[1].

分子量

425.57

Formula

C24H35N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5-HT2A/5-HT2C inverse agonist 1 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-HT2A/5-HT2C inverse agonist 12718990-76-05-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptor5-HT2A receptor5-HT2C receptorhERGcardiovascular risksantipsychotic efficacymousepsychosisInhibitorinhibitorinhibit

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