2. GPCR/G Protein
  3. P2Y Receptor
  4. 5-OMe-UDP

5-OMe-UDP  (Synonyms: 5-Methoxyuridine 5'-trihydrogen diphosphate)

目录号: HY-108663
产品使用指南

摩尔计算器

5-OMe-UDP (5-Methoxyuridine 5'-trihydrogen diphosphate) 是一种 P2Y6 受体激动剂 (EC50=0.08 μM)。5-OMe-UDP 通过与 P2Y6 受体结合，激活该受体，从而触发细胞内的信号传导途径。这种激活可以导致细胞内钙离子浓度的增加，进而调节细胞功能。5-OMe-UDP 的甲氧基团提供了额外的活性和选择性，有助于 5-OMe-UDP 与 P2Y6 受体的结合。5-OMe-UDP 可用于研究与 P2Y6 受体功能相关的疾病，如糖尿病，炎症性肠病，阿尔茨海默病等。

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5-OMe-UDP Chemical Structure

5-OMe-UDP Chemical Structure

CAS No. : 1207530-98-0

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5-OMe-UDP 相关抗体

Top Publications Citing Use of Products

查看 P2Y Receptor 亚型特异性产品:

查看所有亚型
P2Y1 Receptor P2Y2 Receptor P2Y6 Receptor P2Y12 Receptor P2Y13 Receptor P2Y14 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

5-OMe-UDP (5-methoxyuridine 5'-trihydrogen diphosphate) is a P2Y6 receptor agonist (EC50=0.08 μM). 5-OMe-UDP activates the P2Y6 receptor by binding to it, which triggers signaling pathways within the cell. This activation can lead to an increase in intracellular calcium ion concentration, which in turn regulates cellular function. The methoxy groups of 5-OMe-UDP provide additional activity and selectivity, contributing to the binding of 5-OMe-UDP to the P2Y6 receptor. 5-OMe-UDP can be used to study diseases related to P2Y6 receptor function, such as diabetes, inflammatory bowel disease, Alzheimer's disease, etc[1].

IC50 & Target[1]

P2Y6 Receptor

0.08 μM (EC50)

分子量

434.19

Formula

C10H16N2O13P2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5-OMe-UDP 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-OMe-UDP1207530-98-05-Methoxyuridine 5'-trihydrogen diphosphateP2Y ReceptorAgonistP2YDiabetes mellitusAlzheimer's disease1321N1 astrocytoma cellsInhibitorinhibitorinhibit

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