1. Anti-infection
  2. Bacterial
  3. 6,8-Diprenylgenistein

6,8-Diprenylgenistein 是从杜仲中分离得到的一种异黄酮类化合物。6,8-Diprenylgenistein 具有抗微生物和抗肥胖活性。6,8-Diprenylgenistein 可抑制重组人血管内皮生长因子-A 诱导的 HLMEC 的增殖、迁移和管状形成。6,8-Diprenylgenistein 可用于研究预防和治疗口腔癌转移的新型治疗药物。

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6,8-Diprenylgenistein Chemical Structure

6,8-Diprenylgenistein Chemical Structure

CAS No. : 51225-28-6

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规格 价格 是否有货 数量
1 mg ¥6480
3 - 4 周
5 mg   询价  
10 mg   询价  

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

6,8-Diprenylgenistein is an isoflavone compound isolated from Cudrania tricuspidata. 6,8-Diprenylgenistein has antimicrobial and anti-obesity activity. 6,8-Diprenylgenistein inhibits the proliferation, migration and tubular formation of HLMEC induced by recombinant human vascular endothelial growth factor-A. 6,8-Diprenylgenistein can be used to study new therapeutic drugs for the prevention and treatment of oral cancer metastasis [1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MCF7 IC50
8.58 μM
Compound: 38
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay
[PMID: 28522265]
RAW264.7 IC50
19.2 μM
Compound: 10
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells by Griess assay
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells by Griess assay
[PMID: 19113968]
SW480 IC50
8.08 μM
Compound: 38
Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay
Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay
[PMID: 28522265]
分子量

406.47

Formula

C25H26O5

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
6,8-Diprenylgenistein
目录号:
HY-N2692
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