2. 天然产物
  3. 疾病研究领域 植物 萜类
  4. 红豆杉科 癌症
  5. 东北红豆杉
  6. 7-Xylosyl-10-Deacetyltaxol C

7-Xylosyl-10-Deacetyltaxol C  (Synonyms: 7-Xylosyl-10-Deacetylpaclitaxel C)

目录号: HY-N7777
产品使用指南

摩尔计算器

7-Xylosyl-10-Deacetyltaxol C (7-Xylosyl-10-Deacetylpaclitaxel C) 是一种来源于 T. cuspidate 的紫杉醇衍生物，具有抗肿瘤活性，可以抑制 S180 肉瘤的生长。

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7-Xylosyl-10-Deacetyltaxol C Chemical Structure

7-Xylosyl-10-Deacetyltaxol C Chemical Structure

CAS No. : 90332-65-3

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7-Xylosyl-10-Deacetyltaxol C 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

7-Xylosyl-10-Deacetyltaxol C (7-Xylosyl-10-Deacetylpaclitaxel C) is a paclitaxel derivative derived from T. cuspidate. 7-Xylosyl-10-Deacetyltaxol C has anti-tumor activity and inhibits the growth of S180 sarcoma[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A2780 IC50
1.5 μM
Compound: 11
Antiproliferative activity against human A2780 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A2780 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
A549 IC50
0.64 μM
Compound: 11
Antiproliferative activity against human A549/CDDP cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A549/CDDP cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
A549 IC50
19 μM
Compound: 11
Antiproliferative activity against human A549 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A549 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
HCT-8 IC50
8.5 μM
Compound: 11
Antiproliferative activity against human HCT8 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HCT8 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
HeLa IC50
0.05 μM
Compound: 25
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 dye based assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 dye based assay
[PMID: 28240909]
HepG2 IC50
> 25 μM
Compound: 11
Antiproliferative activity against human HepG2 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HepG2 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
MCF7 IC50
> 25 μM
Compound: 11
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
NIH3T3 IC50
> 25 μM
Compound: 11
Antiproliferative activity against mouse NIH/3T3 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against mouse NIH/3T3 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
SW480 IC50
> 25 μM
Compound: 11
Antiproliferative activity against human SW480 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human SW480 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
分子量

938.02

Formula

C49H63NO17
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

7-Xylosyl-10-Deacetyltaxol C 相关分类

  • 摩尔计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-Xylosyl-10-Deacetyltaxol C90332-65-37-Xylosyl-10-Deacetylpaclitaxel COthersT. cuspidatepaclitaxel derivativeanti-tumorS180 sarcomaInhibitorinhibitorinhibit

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