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  3. 7ETMC

7ETMC 是一种细胞色素P450抑制剂,具有选择性抑制人细胞色素P450s 1A1和1A2的活性。7ETMC对P450s 1A1和1A2具有抑制作用,在最初六分钟内IC??值分别为0.46μM和0.50μM,对P450s 2A6和2B1无抑制活性,除7-乙炔基-3-甲基-4-苯基香豆素外,其余抑制剂对P450s 1A1和1A2表现出基于机制的抑制作用。

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7ETMC Chemical Structure

7ETMC Chemical Structure

CAS No. : 1370702-83-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

7ETMC is a cytochrome P450 inhibitor with selective inhibition of human cytochrome P450s 1A1 and 1A2. 7ETMC has inhibitory effects on P450s 1A1 and 1A2 with IC?? values of 0.46μM and 0.50μM, respectively, within the first six minutes, and has no inhibitory activity against P450s 2A6 and 2B1. Except for 7-ethynyl-3-methyl-4-phenylcoumarin, the remaining inhibitors show mechanism-based inhibition of P450s 1A1 and 1A2.

分子量

212.24

Formula

C14H12O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

7ETMC 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
7ETMC
目录号:
HY-115824
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