2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. 8-CPT-2'-O-Me-cAMP

8-CPT-2'-O-Me-cAMP 是一种 Rap1 激活剂。8-CPT-2'-O-Me-cAMP 可增强视网膜色素上皮屏障，抵御黄斑变性中发生的病理性脉络膜内皮细胞侵袭。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

8-CPT-2'-O-Me-cAMP Chemical Structure

8-CPT-2'-O-Me-cAMP Chemical Structure

CAS No. : 510774-50-2

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

8-CPT-2'-O-Me-cAMP 的其他形式现货产品:

Customer Review

Other Forms of 8-CPT-2'-O-Me-cAMP:

8-CPT-2'-O-Me-cAMP 相关抗体

Top Publications Citing Use of Products

查看 Ras 亚型特异性产品:

查看所有亚型
K-Ras H-Ras N-Ras Ras

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

8-CPT-2'-O-Me-cAMP is a Rap1 activator. 8-CPT-2'-O-Me-cAMP enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration[1].

IC50 & Target

Rap1[1]
体外研究
(In Vitro)

8-CPT-2'-O-Me-cAMP (250 µM; 1 h) 诱导 Rap1 活化并增强视网膜色素上皮细胞中连接蛋白和皮质 F-肌动蛋白的募集[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

8-CPT-2'-O-Me-cAMP 相关抗体:
体内研究
(In Vivo)

8-CPT-2'-O-Me-cAMP (2.05µM; 1 µL; intravitreal injection) 可抑制激光损伤模型中脉络膜新生血管病变的发展[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wild type (WT) C57/Bl6 mice (choroidal neovascularization (CNV) model) [1]
Dosage: 2.05µM; 1 µL
Administration: Intravitreal injection
Result: Induced a slight increase in F-actin localization to the cell periphery, and reorganized cell junctions to a more linear shape, dose-dependent decreased in CNV volume, increased Rap1 activity in isolated RPE/choroids.
分子量

485.84

Formula

C17H17ClN5O6PS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

8-CPT-2'-O-Me-cAMP 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

8-CPT-2'-O-Me-cAMP510774-50-2Rasretinal pigment epithelium barrierF-actinchoroidal neovascularizationInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
8-CPT-2'-O-Me-cAMP
目录号：
HY-116312
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z