2. Anti-infection
  3. Bacterial Antibiotic
  4. Ampicillin

Ampicillin  (Synonyms: 氨苄西林; D-(-)-α-Aminobenzylpenicillin)

目录号: HY-B0522 纯度: 99.92%
COA 产品使用指南

摩尔计算器

Ampicillin是一种广谱β-内酰胺抗生素，适用于各种革兰氏阳性和革兰氏阴性菌。

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Ampicillin Chemical Structure

Ampicillin Chemical Structure

CAS No. : 69-53-4

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规格 价格 是否有货 数量
500 mg ￥600
In-stock
1 g ￥950
In-stock
5 g ￥1300
In-stock
10 g   询价  
50 g   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Ampicillin:

Ampicillin 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 45 篇科研文献

查看 Antibiotic 亚型特异性产品:

查看所有亚型
Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

IC50 & Target

β-lactam

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 CC50
> 100 μM
Compound: Ampicillin
Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay
Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay
[PMID: 30392371]
体外研究
(In Vitro)

Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Ampicillin 相关抗体:
体内研究
(In Vivo)

Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig[1]. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood[2]. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

349.40

Formula

C16H19N3O4S
CAS 号
性状

固体

颜色

White to off-white

中文名称

氨苄西林；氨苄青霉素；阿苄西林；胺苄青霉素；氨苄青；安比西林；氨必西林
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
细胞实验： 

H2O 中的溶解度 : 4.9 mg/mL (14.02 mM; ultrasonic and warming and adjust pH to 9 with NaOH and heat to 60°C)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.8620 mL 14.3102 mL 28.6205 mL
5 mM 0.5724 mL 2.8620 mL 5.7241 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料

纯度: 99.92%

COA (285 KB) LCMS (87 KB)

产品使用指南 (1538 KB)
参考文献
Animal Administration
[3]

Mice: Ampicillin is dissolved in normal saline. Male C57BL/6 mice were anesthetized with halothane and subjected to bilateral common carotid artery occlusion for 40 min. Before transient forebrain ischemia, ampicillin (200 mg/kg, intraperitoneally [i.p.]) or penicillin G (6,000 U/kg or 20,000 U/kg, i.p.) was administered daily for 5 days. In the control animals, saline was administered at the same volume and time schedule[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Ampicillin 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.8620 mL 14.3102 mL 28.6205 mL 71.5512 mL
5 mM 0.5724 mL 2.8620 mL 5.7241 mL 14.3102 mL
10 mM 0.2862 mL 1.4310 mL 2.8620 mL 7.1551 mL

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ampicillin69-53-4D-(-)-α-Aminobenzylpenicillin氨苄西林氨苄青霉素阿苄西林胺苄青霉素氨苄青安比西林氨必西林BacterialAntibioticInhibitorinhibitorinhibit

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