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Camobucol  (Synonyms: AGIX 4207)

目录号: HY-14916 纯度: 99.52%
COA 产品使用指南

摩尔计算器

Camobucol (AGIX 4207) 是一种可口服的酚类抗氧化剂和抗炎剂，用于风湿病的研究。

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Camobucol Chemical Structure

Camobucol Chemical Structure

CAS No. : 216167-92-9

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规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥5059
In-stock
1 mg ￥1818
In-stock
5 mg ￥4000
In-stock
10 mg 现货 询价
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Camobucol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Camobucol (AGIX 4207) is an orally active, phenolic antioxidant and anti-inflammatory compound with antirheumatic properties.

体外研究
(In Vitro)

Camobucol exhibits potent antioxidant activity toward lipid peroxides in vitro and displays enhanced cellular uptake. Camobucol selectively inhibits tumor necrosis factor (TNF)-α-inducible levels of the redox-sensitive genes, vascular cell adhesion molecule-1 and monocyte chemoattractant protein-1, with less inhibition of E-selectin, and no effect on intracellular adhesion molecule-1 expression in endothelial cells. In addition, Camobucol inhibits cytokine-induced levels of monocyte chemoattractant protein-1, interleukin (IL)-6, and IL-8 from endothelial cells and human fibroblast-like synoviocytes as well as lipopolysaccharide-induced release of TNF-α, IL-1β, and IL-6 from human peripheral blood mononuclear cells. Camobucol does not inhibit TNF-α-induced nuclear translocation of nuclear factor of the κ-enhancer in B cells (NF-κB), suggesting that the mechanism of action is independent of this redox-sensitive transcription factor[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Camobucol 相关抗体:
分子量

574.88

Formula

C33H50O4S2
CAS 号
性状

固体

颜色

White to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 100 mg/mL (173.95 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.7395 mL 8.6975 mL 17.3949 mL
5 mM 0.3479 mL 1.7395 mL 3.4790 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.52%

COA (193 KB) HNMR (137 KB) RP-HPLC (167 KB) LCMS (355 KB)

产品使用指南 (1538 KB)
参考文献

Camobucol 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7395 mL 8.6975 mL 17.3949 mL 43.4873 mL
5 mM 0.3479 mL 1.7395 mL 3.4790 mL 8.6975 mL
10 mM 0.1739 mL 0.8697 mL 1.7395 mL 4.3487 mL
15 mM 0.1160 mL 0.5798 mL 1.1597 mL 2.8992 mL
20 mM 0.0870 mL 0.4349 mL 0.8697 mL 2.1744 mL
25 mM 0.0696 mL 0.3479 mL 0.6958 mL 1.7395 mL
30 mM 0.0580 mL 0.2899 mL 0.5798 mL 1.4496 mL
40 mM 0.0435 mL 0.2174 mL 0.4349 mL 1.0872 mL
50 mM 0.0348 mL 0.1739 mL 0.3479 mL 0.8697 mL
60 mM 0.0290 mL 0.1450 mL 0.2899 mL 0.7248 mL
80 mM 0.0217 mL 0.1087 mL 0.2174 mL 0.5436 mL
100 mM 0.0174 mL 0.0870 mL 0.1739 mL 0.4349 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Camobucol216167-92-9AGIX 4207AGIX4207AGIX-4207OthersInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-14916
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