2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 根据产品特点分类
  6. 抗辐射化合物库
抗辐射化合物库 - Radioprotector Library

Cat. No.: HY-L178

放射性疾病是人体受各种电离辐射后发生的各种类型和不同程度的损伤 (或疾病) 的总称。即使是少量的电离辐射也会使机体产生自由基和活性氧，引起氧化应激，导致 DNA 损伤和染色体畸变。抗辐射药物又称辐射防护药，是用于预防/保护非肿瘤细胞免受辐射有害影响的化合物。抗辐射药物可预防放射性物质对人体的损伤，减轻各种放射性疾病的临床症状。此外，抗辐射药物还被常运用于癌症放射治疗中,保护正常细胞不受损伤。而理想的抗辐射药物应当在保护正常细胞的前提下，不影响肿瘤细胞对放射治疗的敏感性。

MCE 精心收录了 1,944 个可能具有抗辐射作用的化合物，是放射性疾病、放射治疗药物联合给药研究的有效工具。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 抗辐射化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，1,896 个产品以 10 mM 浓度提供，35 个产品以 2 mM 浓度提供，13 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 1,944 radioprotectors for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of anti-radiation sickness and radiation therapy compounds.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 1,944 bioactive compounds with definite or potential radiation resistance supplied as pre-dissolved Solutions or Solid.
Solution: 1,896 compounds supplied in 10 mM solution, 35 compounds supplied in 2 mM solution, 13 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

NF-κB (278)

COX (218)

mTOR (108)

AMPK (78)

PI3K (56)

CXCR (41)

Akt (39)

HIV (32)

ERK (25)

PPAR (22)

MMP (19)

STAT (18)

HSV (12)

JAK (12)

JNK (12)

HBV (10)

IFNAR (10)

VEGFR (10)

PARP (9)

HDAC (7)

IKK (7)

Wnt (7)

HCV (6)

HSP (6)

SOD (6)

AP-1 (5)

CDK (5)

EGFR (5)

FAK (5)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Radioprotector Library
    目录号：
    HY-L178
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