2. Membrane Transporter/Ion Channel Anti-infection
  3. Proton Pump Bacterial
  4. Esomeprazole potassium salt

Esomeprazole potassium salt  (Synonyms: 艾美拉唑钾盐; (S)-Omeprazole potassium salt; (-)-Omeprazole potassium salt)

目录号: HY-17021B 纯度: 98.18%
COA 产品使用指南

摩尔计算器

Esomeprazole potassium salt ((S)-Omeprazole potassium salt) 是一种有效的具有口服活性质子泵抑制剂，可通过抑制胃壁细胞中的 H+, K+-ATPase 来降低酸分泌，并可用于胃食管反流疾病的研究。

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Esomeprazole potassium salt Chemical Structure

Esomeprazole potassium salt Chemical Structure

CAS No. : 161796-84-5

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规格 价格 是否有货 数量
1 mg ￥990
In-stock
5 mg ￥2565
In-stock
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

Other Forms of Esomeprazole potassium salt:

Esomeprazole potassium salt 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole potassium salt has the potential for symptomatic gastroesophageal reflux disease research[1][2][3].

IC50 & Target

H+, K+-ATPase[1][2]
体外研究
(In Vitro)

Esomeprazole (25-100 µM; 20 hours; MDA-MB-468 cells) treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Esomeprazole potassium salt 相关抗体:

Cell Viability Assay[1]

Cell Line: MDA-MB-468 cells
Concentration: 25 µM, 50 µM, 75 µM, 100 µM
Incubation Time: 20 hours
Result: Suppressed growth of triple-negative breast cancer cell in vitro in a dose-dependent manner.
体内研究
(In Vivo)

Esomeprazole (30-300 mg/kg; oral gavage; daily; for 19 or 11 days; C57BL/6J mice) treatment significantly inhibits the progression of fibrosis throughout the lungs of the animals. Esomeprazole also reduces circulating markers of inflammation and fibrosis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL/6J mice (8-weeks old, 25-30 g) treated with cotton smoke-induced lung injury[2]
Dosage: 30 mg/kg, 300 mg/kg
Administration: Oral gavage; daily; for 19 or 11 days
Result: Significantly inhibited the progression of fibrosis throughout the lungs of the animals.
Clinical Trial
分子量

383.51

Formula

C17H18KN3O3S
CAS 号
性状

固体

颜色

White to off-white

中文名称

埃索美拉唑钾盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light, stored under nitrogen

*该产品在溶液状态不稳定，建议您现用现配，即刻使用。

溶解性数据
细胞实验： 

DMSO 中的溶解度 : 38.35 mg/mL (100.00 mM; 超声加热助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.6075 mL 13.0375 mL 26.0749 mL
5 mM 0.5215 mL 2.6075 mL 5.2150 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液；该产品在溶液状态不稳定，建议您现用现配，即刻使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Esomeprazole potassium salt 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液；该产品在溶液状态不稳定，建议您现用现配，即刻使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6075 mL 13.0375 mL 26.0749 mL 65.1873 mL
5 mM 0.5215 mL 2.6075 mL 5.2150 mL 13.0375 mL
10 mM 0.2607 mL 1.3037 mL 2.6075 mL 6.5187 mL
15 mM 0.1738 mL 0.8692 mL 1.7383 mL 4.3458 mL
20 mM 0.1304 mL 0.6519 mL 1.3037 mL 3.2594 mL
25 mM 0.1043 mL 0.5215 mL 1.0430 mL 2.6075 mL
30 mM 0.0869 mL 0.4346 mL 0.8692 mL 2.1729 mL
40 mM 0.0652 mL 0.3259 mL 0.6519 mL 1.6297 mL
50 mM 0.0521 mL 0.2607 mL 0.5215 mL 1.3037 mL
60 mM 0.0435 mL 0.2173 mL 0.4346 mL 1.0865 mL
80 mM 0.0326 mL 0.1630 mL 0.3259 mL 0.8148 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Esomeprazole161796-84-5(S)-Omeprazole(-)-Omeprazole埃索美拉唑钾盐Proton PumpBacterialCYP3A4H+K+-ATPaseantacidanti-inflammationfibrosisgastroesophagealInhibitorinhibitorinhibit

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目录号：
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