2. Membrane Transporter/Ion Channel Anti-infection
  3. Proton Pump Bacterial
  4. Esomeprazole hemistrontium

Esomeprazole hemistrontium  (Synonyms: (S)-Omeprazole hemistrontium; (-)-Omeprazole hemistrontium)

目录号: HY-17021C
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摩尔计算器

Esomeprazole ((S)-Omeprazole) hemistrontium 是一种有效的具有口服活性质子泵 (proton pump) 抑制剂，可通过抑制胃壁细胞中的 H+, K+-ATPase 来降低酸分泌，并可用于胃食管反流疾病的研究。

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Esomeprazole hemistrontium Chemical Structure

Esomeprazole hemistrontium Chemical Structure

CAS No. : 914613-86-8

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Esomeprazole hemistrontium 的其他形式现货产品:

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Other Forms of Esomeprazole hemistrontium:

Esomeprazole hemistrontium 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Esomeprazole ((S)-Omeprazole) hemistrontium is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole hemistrontium has the potential for symptomatic gastroesophageal reflux disease research[1][2][3].

体外研究
(In Vitro)

Esomeprazole (25-100 µM; 20 hours; MDA-MB-468 cells) hemistrontium treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Esomeprazole hemistrontium 相关抗体:

Cell Viability Assay[1]

Cell Line: MDA-MB-468 cells
Concentration: 25 µM, 50 µM, 75 µM, 100 µM
Incubation Time: 20 hours
Result: Suppressed growth of triple-negative breast cancer cell in vitro in a dose-dependent manner.
体内研究
(In Vivo)

Esomeprazole (30-300 mg/kg; oral gavage; daily; for 19 or 11 days; C57BL/6J mice) hemistrontium treatment significantly inhibits the progression of fibrosis throughout the lungs of the animals. Esomeprazole also reduces circulating markers of inflammation and fibrosis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL/6J mice (8-weeks old, 25-30 g) treated with cotton smoke-induced lung injury[2]
Dosage: 30 mg/kg, 300 mg/kg
Administration: Oral gavage; daily; for 19 or 11 days
Result: Significantly inhibited the progression of fibrosis throughout the lungs of the animals.
Clinical Trial
分子量

388.22

Formula

C17H18N3O3SSr+
CAS 号
中文名称

埃索美拉唑锶
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Esomeprazole hemistrontium 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Esomeprazole hemistrontium914613-86-8(S)-Omeprazole hemistrontium(-)-Omeprazole hemistrontium埃索美拉唑锶Proton PumpBacterialCYP3A4H+K+-ATPaseantacidanti-inflammationfibrosisgastroesophagealInhibitorinhibitorinhibit

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