2. 天然产物
  3. 疾病研究领域 植物 生物碱
  4. 豆科 炎症/免疫 吲哚类生物碱
  5. 相思子
  6. L-(+)-Abrine

L-(+)-Abrine  (Synonyms: L-(+)-红豆碱; L-Abrine; L-N-Methyltryptophan; N-α-Methyl-L-tryptophan)

目录号: HY-N1436 纯度: 99.76%
COA 产品使用指南

摩尔计算器

L-(+)-Abrine 是在 Abrus precatorius 种子中发现的一种致命白蛋白，是一种急性毒性生物碱，可用作化学标记物。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

L-(+)-Abrine Chemical Structure

L-(+)-Abrine Chemical Structure

CAS No. : 526-31-8

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
50 mg ￥500
In-stock
100 mg ￥800
In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Customer Review

L-(+)-Abrine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

L-(+)-Abrine, a lethal albumin found in Abrus precatorius seeds, is an acute toxic alkaloid and chemical marker for abrin.

体外研究
(In Vitro)

L-(+)-Abrine is a marker for abrin poisoning. A strong indication for abrin poisoning is the presence of the chemical maker L-(+)-Abrine, which can survive metabolism in significant amounts making it detectable in human urine[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

L-(+)-Abrine 相关抗体:
体内研究
(In Vivo)

Abrin is a toxic protein found in the jequirity seed. L-(+)-Abrine (L-Abrine) is also found in the jequirity seed and can be used as a biomarker for abrin exposure. An animal study is designed to monitor the excretion and recovery of L-(+)-Abrine in 20 rats. The animals are exposed to one of three concentrations of L-(+)-Abrine, a single high concentration of L-tryptophan, or no agent (control). The low L-(+)-Abrine dose corresponds to 0.63 LD50 i.p. abrin in mice, assuming a concentration ratio of 1:4 of abrin to L-(+)-Abrine and an LD50 for abrin of 20 μg/kg. The mid and high L-(+)-Abrine (250 and 400 μg/kg) doses are included to ensure that the target analyte can be detected and tracked over the course of the experiment[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

218.25

Formula

C12H14N2O2
CAS 号
性状

固体

颜色

Off-white to light yellow

中文名称

L-(+)-相思子碱；L-(+)-相思豆碱；L-(+)-红豆碱
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

H2O 中的溶解度 : 1.85 mg/mL (8.48 mM; ultrasonic and adjust pH to 10 with NaOH)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.5819 mL 22.9095 mL 45.8190 mL
5 mM 0.9164 mL 4.5819 mL 9.1638 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料

纯度: 99.76%

COA (291 KB) HNMR (210 KB) LCMS (119 KB)

产品使用指南 (1538 KB)
参考文献
Animal Administration
[2]

Rats[2]
Twenty male Wistar rats, approximately 6-7 weeks of age and weighing approximately 175-200 g upon receipt, are used. A total of 12 rats are dosed intramuscularly with L-(+)-Abrine at 0.63, 3.13, and 5 times the expected Abrin LD50 of 20 μg/kg. Although no toxin is used here, the concentration of the biomarker is increased by a factor of 4 to estimate an equivalent level of toxin, assuming that Labrine is present in rosary peas at a concentration four times greater that the toxin abrin. A total of 12 rats are dosed intramuscularly with L-(+)-Abrine: four at approximately 50 μg/kg body weight (bw), four at 250 μg/kg bw, and four at 400 μg/kg bw. Four control rats are dosed with water, which is the vehicle for all dosing experiments. Another four rats are dosed intraperitoneally with 20,000 μg/kg L-tryptophan to verify that endogenous L-tryptophan is not metabolized to L-(+)-Abrine[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

L-(+)-Abrine 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.5819 mL 22.9095 mL 45.8190 mL 114.5475 mL
5 mM 0.9164 mL 4.5819 mL 9.1638 mL 22.9095 mL

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-(+)-Abrine526-31-8L-Abrine L-N-Methyltryptophan N-α-Methyl-L-tryptophanL-(+)-相思子碱L-(+)-相思豆碱L-(+)-红豆碱OthersInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
L-(+)-Abrine
目录号：
HY-N1436
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z