2. Anti-infection
  3. Parasite
  4. Melarsonyl

Melarsonyl  (Synonyms: Melarsonic acid)

目录号: HY-U00295
产品使用指南

摩尔计算器

Melarsonyl (Melarsonic acid) 是一种驱虫剂，可有效抑制寄生虫 (parasite)。

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Melarsonyl Chemical Structure

Melarsonyl Chemical Structure

CAS No. : 37526-80-0

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Other Forms of Melarsonyl:

Melarsonyl 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

查看所有亚型
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.

IC50 & Target

Parasite[1]
体内研究
(In Vivo)

For acute infections produced by T. brucei brucei GVR, Potassium Melarsonyl exhibits trypanocidal activities. Potassium Melarsonyl (Trimelarsan) cures less than 50% mice at a dose of 25 μmol/kg for 4 consecutive days. At 60 μmol/kg, it cures all the mice in a chronic-infection model[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

456.33

Formula

C13H13AsN6O4S2
CAS 号
性状

固体

颜色

Light yellow to yellow

中文名称

美拉胂
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献
Animal Administration
[1]

Mice[1]

Mice are infected i.p. with 104 bloodstream trypomastigotes taken from an infected mouse and suspended in 0.1 mL of phosphate-buffered saline, pH 7.2. The infection is allowed to develop for 24 h before treatment is begun. Ten infected mice are used as controls and received only excipient, 1% carboxymethylcellulose by the i.p. route in a 0.1 ml volume. The other mice receive a single dose of the diluted or suspended Potassium Melarsonyl (20, 40, 60 μmol/kg) in the same manner. Six mice are used per dose. The trypanocidal activity is evaluated by the mean survival time of treated mice for each dose[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Melarsonyl 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Melarsonyl37526-80-0Melarsonic acid美拉胂ParasiteInhibitorinhibitorinhibit

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