1. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Histamine Receptor
  3. Rocastine

Rocastine  (Synonyms: AHR-11325)

目录号: HY-101745
产品使用指南

Rocastine 是一种选择性的,非镇静的 H1 拮抗剂,为抗组胺剂。

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Rocastine Chemical Structure

Rocastine Chemical Structure

CAS No. : 91833-49-7

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规格 是否有货
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rocastine is a selective, nonsedating H1 antagonist, acting as an antihistamine.

体内研究
(In Vivo)

Rocastine is effective with a 15 min pretreatment time (PD50 = 0.13 mg/kg) as it is with a 1 hr pretreatment time (PD50 = 0.12 mg/kg). Rocastine protects guinea pigs from collapse induced by aerosolized antigen; rocastine is approximately 36x more potent than diphenhydramine and as potent as oxatomide and terfenadine. Rocastine does not alter the EEG of cats at doses in vast excess (150x) of its antihistaminic dose nor does it potentiate yohimbine toxicity in mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

265.37

Formula

C13H19N3OS

CAS 号
中文名称

罗卡斯汀

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Rocastine
目录号:
HY-101745
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