2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Sialyltransferase

Sialyltransferase (唾液酸转移酶)

Sialyltransferase

唾液酸转移酶是将唾液酸转移到新生寡糖上的酶。唾液酸转移酶 (SiaT) 表现出不同的特性和偏好，例如对底物和糖苷键的偏好。唾液酸转移酶使用胞苷单磷酸 N-乙酰神经氨酰 (CMP-Neu5Ac) 作为活化糖供体。唾液酸转移酶的过度表达与肿瘤高唾液酸化和不良预后有关[1]。

Sialyltransferases are enzymes that transfer sialic acid to nascent oligosaccharides. Sialyltransferases (SiaTs) exhibit distinct characteristics and preferences, such as for substrates and glycosidic linkages. Sialyltransferases use cytidine monophosphate N-acetylneuraminic acid (CMP-Neu5Ac) as an activated sugar donor. Overexpression of sialyltransferases is associated with tumor hypersialylation and poor outcome[1].

Sialyltransferase 相关产品 (10):

Cat. No. Product Name Effect Purity Chemical Structure
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