2. Metabolic Enzyme/Protease GPCR/G Protein
  3. Lipoxygenase Leukotriene Receptor
  4. A63162

A63162 是一种特异性的 5-脂氧合酶 (5-LOX) 抑制剂。A63162 抑制有丝分裂原 (PHA)诱导的马单核细胞 (BMC) 增殖，并在相同浓度下抑制 Calcimycin (HY-N6687) 诱导的白三烯 LTB4 合成。A63162 可用于慢性阻塞性肺病、关节炎和炎症性肠道疾病的研究。

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A63162 Chemical Structure

A63162 Chemical Structure

CAS No. : 111525-11-2

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A63162 相关抗体

Top Publications Citing Use of Products

查看 Lipoxygenase 亚型特异性产品:

查看所有亚型
5-LOX 12-LOX 15-LOX

查看 Leukotriene Receptor 亚型特异性产品:

查看所有亚型
LTB4 LTC4/CysLT2 LTD4/CysLT1 LTE4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

A63162 is a specific 5-lipoxygenase (5-LOX) inhibitor. A63162 inhibits mitogen (PHA)-induced horse mononuclear cell (BMC) proliferation and inhibits Calcimycin (HY-N6687)-induced leukotriene LTB4 synthesis at the same concentration. A63162 can be used in the study of chronic obstructive pulmonary disease, arthritis and inflammatory bowel disease[1].

分子量

285.34

Formula

C17H19NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

A63162 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A63162111525-11-2A 63162A-63162LipoxygenaseLeukotriene ReceptorLOXInhibitorslipoxygenasemonocytesleukotrienesinflammationInhibitorinhibitorinhibit

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