2. GPCR/G Protein
  3. Endothelin Receptor
  4. ACT-373898

ACT-373898 是 Macitentan 的一种非活性羧酸代谢物。Macitentan 是一种具有口服活性，非多肽 ETA 和 ETB (内皮素受体) 双拮抗剂。

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ACT-373898 Chemical Structure

ACT-373898 Chemical Structure

CAS No. : 1433875-14-9

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ACT-373898 相关抗体

Top Publications Citing Use of Products

查看 Endothelin Receptor 亚型特异性产品:

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ETA ETB

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ACT-373898 is an inactive carboxylic acid metabolite of Macitentan. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist[1].

体外研究
(In Vitro)

The elimination half-life (t1/2) is approximately 16 h for Macitentan, and ACT-373898 has a similar pharmacokinetic (PK) profile to Macitentan[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

ACT-373898 相关抗体:
分子量

445.29

Formula

C15H17BrN4O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ACT-373898 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ACT-3738981433875-14-9ACT373898ACT 373898Endothelin ReceptorMacitentancarboxylicacidmetaboliteendothelinInhibitorinhibitorinhibit

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产品名称：
ACT-373898
目录号：
HY-135500
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