1. Apoptosis Anti-infection
  2. TNF Receptor Bacterial
  3. Adalimumab (Powder)

Adalimumab (Powder) 

目录号: HY-P9S0009

Adalimumab (Powder) 是一种人源的单克隆 IgG1 抗体,靶向肿瘤坏死因子α (TNF-α)。

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Adalimumab (Powder) Chemical Structure

Adalimumab (Powder) Chemical Structure

CAS No. : 331731-18-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Adalimumab (Powder) is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α)[1][2].

体外研究
(In Vitro)

使用 Adalimumab 处理 HUVEC 长达 12 小时,显示对其细胞活力没有不利影响,即使 Adalimumab 的浓度比本研究中使用的浓度高 10 倍[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Adalimumab 的消除半衰期很长 (t1/2=~20 天)[1]
荧光标记的 Adalimumab 富集主要在油红 O 阳性病变中观察到,证明药物进入动脉粥样硬化斑块的良好组织渗透性,在溶剂对照注射到高胆固醇血症 Ldlr-/- 老鼠后,血管壁无背景荧光[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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