2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. AF-DX 384 methanesulfonate

AF-DX 384 (methanesulfonate) 是 M2 和 M4 毒蕈碱乙酰胆碱受体的选择性拮抗剂 ，Ki 分别为 6.03 nM 和 10 nM。AF-DX 384 (methanesulfonate) 可逆转老年大鼠以及东莨菪碱诱导的幼鼠在新物体识别和被动回避方面的缺陷。

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AF-DX 384 methanesulfonate Chemical Structure

AF-DX 384 methanesulfonate Chemical Structure

CAS No. : 118290-27-0

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Other Forms of AF-DX 384 methanesulfonate:

AF-DX 384 methanesulfonate 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

AF-DX 384 (methanesulfonate) is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors (Kis=6.03 and 10 nM, respectively)[1]. AF-DX 384 (methanesulfonate) reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine[2].

分子量

574.74

Formula

C28H42N6O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AF-DX 384 methanesulfonate 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AF-DX 384118290-27-0mAChRMuscarinic acetylcholine receptormAChR AntagonistInhibitorinhibitorinhibit

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产品名称：
AF-DX 384 methanesulfonate
目录号：
HY-124223
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