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  3. AIE-Cbz-LD-C7

AIECbz-LD-C7 是一种基于喹啉-丙二腈 (QM) 和咔唑共轭的聚集诱导发射 (AIE) 探针。AIECbz-LD-C7 具有出色的 LD 特异性。AIECbz-LD-C7 可用于跟踪 LDs 的动态变化,研究 LDs 与溶酶体/内质网(ER)的关联。

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AIE-Cbz-LD-C7 Chemical Structure

AIE-Cbz-LD-C7 Chemical Structure

CAS No. : 2810130-33-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AIECbz-LD-C7 is an aggregation-induced emission (AIE) probe based on the conjugation of quinoline-malononitrile (QM) and carbazole. AIECbz-LD-C7 has excellent LD-specificity. AIECbz-LD-C7 can be used for tracking the dynamic changes of LDs and studying the association between LDs and lysosome/endoplasmic reticulum (ER)[1].

体外研究
(In Vitro)

AIE-Cbz-LD-C (0, 2, 5, 10, 20, and 30 μM; 24 h) have excellent biocompatibility[1].
AIECbz-LD-C7 (0.5 μM, 15 min) could aggregate in LDs accurately and light up the LDs with good photostability[1].
AIE-Cbz-LD-C7 (0.5 μM) can be used to visualize the interplay between LDs and lysosomes during lipophag due to the excellent LD-specificity[1].
AIE-Cbz-LD-C7 (0.5 μM, 15 min) increases the number of ferroptosis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: HepG2 cells
Concentration: 0, 2, 5, 10, 20, and 30 μM
Incubation Time: 24 h
Result: Displayed favorable viability with a value above 90%.
分子量

510.67

Formula

C35H34N4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

AIE-Cbz-LD-C7 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
AIE-Cbz-LD-C7
目录号:
HY-151468
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