2. Metabolic Enzyme/Protease
  3. Phospholipase
  4. AK106-001616

AK106-001616 是一种强效的且选择性的胞质磷脂酶 A2 (cPLA2) 抑制剂 (IC50=3.8 nmol/L)。AK106-001616 能够减少刺激细胞产生的前列腺素 (PG) E2 和白三烯 (LT) B4。AK106-001616 可用于炎症性疾病，神经性疼痛和肺纤维化的研究。

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AK106-001616 Chemical Structure

AK106-001616 Chemical Structure

CAS No. : 590416-75-4

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AK106-001616 相关抗体

Top Publications Citing Use of Products

查看 Phospholipase 亚型特异性产品:

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Phospholipase A PLD Phospholipase C

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AK106-001616 is a potent and selective inhibitor of cytosolic phospholipase A2 (cPLA2) (IC50=3.8 nmol/L). AK106-001616 is able to reduce the production of prostaglandins (PG) E2 and leukotrienes (LT) B4 by stimulated cells. AK106-001616 can be used in the study of inflammatory diseases, neuropathic pain and pulmonary fibrosis[1].

分子量

427.50

Formula

C26H25N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AK106-001616 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AK106-001616590416-75-4PhospholipaseInhibitorprostaglandinsleukotrieneinflammationneuropathic painpulmonary fibrosiscPLA2inhibitorinhibit

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目录号：
HY-127110
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