2. GPCR/G Protein Neuronal Signaling
  3. Orexin Receptor (OX Receptor)
  4. [Ala11,D-Leu15]-Orexin B(human)

[Ala11,D-Leu15]-Orexin B(human) 

目录号: HY-P1340 纯度: 98.04%
COA 产品使用指南

摩尔计算器

[Ala11,D-Leu15]-Orexin B(human) 是一种有效的，选择性的 orexin-2 receptor (OX2) 的激动剂。[Ala11,D-Leu15]-Orexin B(human) 对 OX2 (EC50=0.13 nM) 比对 OX1 (52 nM) 高出 400 倍的选择性。

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Custom Peptide Synthesis

[Ala11,D-Leu15]-Orexin B(human) Chemical Structure

[Ala11,D-Leu15]-Orexin B(human) Chemical Structure

CAS No. : 532932-99-3

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规格 价格 是否有货 数量
1 mg ￥4200
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Other Forms of [Ala11,D-Leu15]-Orexin B(human):

[Ala11,D-Leu15]-Orexin B(human) 相关抗体

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查看 Orexin Receptor (OX Receptor) 亚型特异性产品:

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OX2 Receptor OX1 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (52 nM)[1].

IC50 & Target[1]

OX2

0.13 nM (EC50)

OX1

52 nM (EC50)

分子量

2857.26

Formula

C120H206N44O35S
CAS 号
性状

固体

颜色

White to off-white

Sequence

Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Sequence Shortening

RSGPPGLQGRAQRLLQASGNHAAGILTM-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

纯度 & 产品资料
参考文献

[Ala11,D-Leu15]-Orexin B(human) 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Ala11,D-Leu15]-Orexin B(human)532932-99-3Orexin Receptor (OX Receptor)Hypocretin ReceptorHCRT ReceptorL-alanineD-aminoacidselectivityneuropeptideInhibitorinhibitorinhibit

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