2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease Antibody-drug Conjugate/ADC Related
  3. HSP ADC Cytotoxin
  4. Aminohexylgeldanamycin hydrochloride

Aminohexylgeldanamycin hydrochloride  (Synonyms: AHGDM hydrochloride)

目录号: HY-133571A
产品使用指南

摩尔计算器

Aminohexylgeldanamycin (AHGDM) hydrochloride，Geldanamycin 的衍生物，是一种热休克蛋白 90 (HSP90) 抑制剂。Aminohexylgeldanamycin hydrochloride 具有抗血管生成和抗肿瘤活性。

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Aminohexylgeldanamycin hydrochloride Chemical Structure

Aminohexylgeldanamycin hydrochloride Chemical Structure

CAS No. : 1146534-45-3

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Aminohexylgeldanamycin hydrochloride 的其他形式现货产品:

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Other Forms of Aminohexylgeldanamycin hydrochloride:

Aminohexylgeldanamycin hydrochloride 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Aminohexylgeldanamycin (AHGDM) hydrochloride, a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin hydrochloride shows antiangiogenic and antitumor activities[1].

IC50 & Target[1]

HSP90

 

体外研究
(In Vitro)

HPMA copolymer-aminohexylgeldanamycin conjugates target cell surface expressed GRP78 in prostate cancer[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Aminohexylgeldanamycin hydrochloride 相关抗体:
分子量

681.26

Formula

C34H53ClN4O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Aminohexylgeldanamycin hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aminohexylgeldanamycin1146534-45-3AHGDMHSPADC CytotoxinHeat shock proteinsADC PayloadantiangiogenicantitumorbenzoquinoneansamycinsconjugatesInhibitorinhibitorinhibit

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