2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Ampullosporin A

Ampullosporin A 是一种可以从真菌 Sepedonium ampullosporum HKI-0053 中分离得到的 peptaibol 型多肽，具有神经阻滞剂样活性。Ampullosporin A 可抑制 NMDA 受体拮抗剂 MK-801 (HY-15084B) 诱导的多动症，并改善药物处理引起的社交行为异常。Ampullosporin A 可以改变谷氨酸受体的活性，而不会影响多巴胺 D1 和 D2 受体。

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Ampullosporin A Chemical Structure

Ampullosporin A Chemical Structure

CAS No. : 197960-94-4

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Ampullosporin A 相关抗体

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  • 生物活性

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生物活性

Ampullosporin A is a peptaibol-type polypeptide that can be isolated from the fungus Sepedonium ampullosporum HKI-0053, exhibiting neuroleptic-like activity. Ampullosporin A can inhibit hyperactivity induced by NMDA receptor antagonist MK-801 (HY-15084B) and ameliorate social behavior abnormalities caused by subchronic drug treatment. Ampullosporin A alters the activity of glutamate receptors without affecting dopamine D1 and D2 receptors[1].

分子量

1622.95

Formula

C77H127N19O19
CAS 号
结构分类
初始来源

Sepedonium ampullosporum HKI-0053
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ampullosporin A 相关分类

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Keywords:

Ampullosporin A197960-94-4iGluRIonotropic glutamate receptorsantipsychotic drugSchizophreniaSepedonium ampullosporum HKI-0053hyperactivitysocial behavior abnormalitiesInhibitorinhibitorinhibit

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