2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. Antazoline phosphate

Antazoline phosphate  (Synonyms: Phenazoline phosphate)

目录号: HY-B1067B
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摩尔计算器

Antazoline phosphate 是一种 H1 受体拮抗剂，影响中枢神经系统的活动，具有抗心律失常作用。

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Antazoline phosphate Chemical Structure

Antazoline phosphate Chemical Structure

CAS No. : 154-68-7

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Antazoline phosphate 的其他形式现货产品:

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Other Forms of Antazoline phosphate:

Antazoline phosphate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antazoline phosphate is an H1 receptor antagonist that affects the activity of the central nervous system, has a potent antiarrhythmic effect[1][2][3].

体外研究
(In Vitro)

Antazoline phosphate shows good inhibitory effect on HBV DNA in the supernatant of HepAD38 and Huh7 cells with the value of EC50 is 2.910 μmol/L and 2.349 μmol/L, respectively[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antazoline phosphate 相关抗体:

Cell Viability Assay[2]

Cell Line: HepAD38 cells
Concentration: 10 μmol/L
Incubation Time: 5 days
Result: Exhibited no significant cytotoxicity at a concentration of 10μmol/L and had a dose-dependent inhibition of HBV DNA in the supernatant.

RT-PCR[2]

Cell Line: Huh7 cells
Concentration: 30 μmol/L, 10 μmol/L, 3.33 μmol/L, 1.1 μmol/L, 0.370 μmol/L, and 0.123 μmol/L
Incubation Time: 4 days
Result: Had a significant inhibitory effect on HBV DNA in supernatants in a dose-dependent manner.
体内研究
(In Vivo)

Antazoline phosphate (IP; 0.01 ml/g; 30min) as H1 receptor antagonists diminishes the anticonvulsant activity of carbamazepine and diphenylhydantoin[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Swiss mice[3]
Dosage: 0.01 mL/g
Administration: IP; 0.01 ml/g; 30min
Result: Showed some proconvulsive activity.
分子量

363.35

Formula

C17H22N3O4P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antazoline phosphate 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antazoline154-68-7PhenazolineHistamine ReceptorH1 receptor antagonistnervous systemInhibitorinhibitorinhibit

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