1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. GABA Receptor Sodium Channel
  3. Anticonvulsant agent 5

Anticonvulsant agent 5 (Compound 5c) 对 GABAA 受体 (GABAA receptor) 和 NaV1.3 受体 (NaV1.3 receptor) 具有高亲和力。Anticonvulsant agent 5 在小鼠精神运动性癫痫试验中表现出抗惊厥活性,ED50 为 107 mg/kg。Anticonvulsant agent 5 对 Kainic acid (HY-N2309) 表现出神经保护活性,IC50 为 113 μM。Anticonvulsant agent 5 具有血脑屏障 (BBB) 通透性。

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Anticonvulsant agent 5 Chemical Structure

Anticonvulsant agent 5 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticonvulsant agent 5 (Compound 5c) exhibits high affinity for GABAA receptors and NaV1.3 receptors. Anticonvulsant agent 5 shows anticonvulsant efficacy in mice psychomotor epilepsy test with an ED50 of 107 mg/kg. Anticonvulsant agent 5 exhibits neuroprotective activity against Kainic acid (HY-N2309) with an IC50 of 113 μM. Anticonvulsant agent 5 is blood-brain barrier (BBB) penetrable[1].

分子量

448.51

Formula

C24H21FN4O2S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anticonvulsant agent 5
目录号:
HY-162757
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