2. MAPK/ERK Pathway NF-κB
  3. NF-κB p38 MAPK
  4. Antidesmone

Antidesmone 是一种异喹啉类生物碱，可从 Antidesma membranaceum 中分离得到。

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Antidesmone Chemical Structure

Antidesmone Chemical Structure

CAS No. : 222629-77-8

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Antidesmone 相关抗体

Top Publications Citing Use of Products

查看 NF-κB 亚型特异性产品:

查看所有亚型
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

查看 p38 MAPK 亚型特异性产品:

查看所有亚型
p38 MAPK p38α p38β MAPK13 p38δ p38γ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antidesmone is a isoquinoline alkaloid that can be isolated from Antidesma membranaceum[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
8.4 μM
Compound: 8
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by SRB assay
[PMID: 32946697]
HeLa IC50
23.4 μg/mL
Compound: 13
Cytotoxicity against human HeLa cells after 48 hrs by SRB assay
Cytotoxicity against human HeLa cells after 48 hrs by SRB assay
[PMID: 26848627]
KB IC50
17.7 μM
Compound: 8
Antiproliferative activity against human KB cells assessed as reduction in cell viability after 72 hrs by SRB assay
Antiproliferative activity against human KB cells assessed as reduction in cell viability after 72 hrs by SRB assay
[PMID: 32946697]
MCF7 IC50
6.4 μM
Compound: 8
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by SRB assay
[PMID: 32946697]
MDA-MB-231 IC50
6.7 μM
Compound: 8
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by SRB assay
[PMID: 32946697]
RAW264.7 IC50
16.1 μM
Compound: 18
Inhibition of NO production in LPS-stimulated mouse RAW264.7 cells preincubated for 15 mins followed by LPS stimulation and measured after 20 hrs by Griess reagent based assay
Inhibition of NO production in LPS-stimulated mouse RAW264.7 cells preincubated for 15 mins followed by LPS stimulation and measured after 20 hrs by Griess reagent based assay
[PMID: 36746775]
分子量

319.44

Formula

C19H29NO3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antidesmone 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antidesmone222629-77-8NF-κBp38 MAPKNuclear factor-κBNuclear factor-kappaBAntidesma membranaceumIsoquinoline alkaloidInhibitorinhibitorinhibit

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