2. Immunology/Inflammation
  3. Interleukin Related
  4. Antiflammin-1

Antiflammin-1  (Synonyms: Uteroglobin(39-47))

目录号: HY-P1931
产品使用指南

摩尔计算器

Antiflammin-1 是一种抗炎肽 1 (MQMKKVLDS)。Antiflammin-1 是子宫珠蛋白的衍生物。Antiflammin-1 在博来霉素 (HY-108345) 诱导的肺损伤中具有抗炎和抗纤维化作用。

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Custom Peptide Synthesis

Antiflammin-1 Chemical Structure

Antiflammin-1 Chemical Structure

CAS No. : 118850-71-8

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

Antiflammin-1 相关抗体

Top Publications Citing Use of Products

查看 Interleukin Related 亚型特异性产品:

查看所有亚型
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antiflammin-1 is an anti-inflammatory peptide 1 (MQMKKVLDS). Antiflammin-1 is a derivative of uteroglobin. Antiflammin-1 has anti-inflammatory and antifibrotic actions in bleomycin (HY-108345)-induced lung injury[1][2][3].

IC50 & Target

IL-1β

 

体外研究
(In Vitro)

Antiflammin-1 (10 μM) 可抑制 TGF-β1 诱导的 NIH3T3 细胞增殖，该增殖由 uteroglobin 受体介导[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antiflammin-1 相关抗体:
体内研究
(In Vivo)

Antiflammin-1 (2-10 mg/kg，腹腔注射，每天，持续 6 天) 可降低博莱霉素治疗小鼠的 TNF-α 和 IL-1β 水平。 Antiflammin-1 在博来霉素 (HY-108345) 诱导的肺损伤中具有抗炎和抗纤维化作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1079.33

Formula

C45H82N12O14S2
CAS 号
Sequence

Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser
Sequence Shortening

MQMKKVLDS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
细胞实验： 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

Antiflammin-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiflammin-1118850-71-8Uteroglobin(39-47)Antiflammin1Antiflammin 1Interleukin RelatedILpulmonary fibrosisNIH3T3 cellsuteroglobinInhibitorinhibitorinhibit

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