2. PI3K/Akt/mTOR Anti-infection
  3. mTOR Fungal
  4. Antifungal agent 106

Antifungal agent 106 (Compound Z31) 是一种苯甲酸衍生物，是针对 Monilinia fructicola 的潜在杀菌剂。Antifungal agent 106 具有抗真菌活性，其 EC50 值为 11.8 mg/L。Antifungal agent 106 通过破坏细胞膜的完整性，导致膜通透性增加和细胞内电解质释放，来影响菌丝正常生长。Antifungal agent 106 可用于石果褐腐病相关研究。

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Antifungal agent 106 Chemical Structure

Antifungal agent 106 Chemical Structure

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Antifungal agent 106 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antifungal agent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide against Monilinia fructicola. Antifungal agent 106 exhibits antifungal activity with an EC50 value of 11.8 mg/L. It affects hyphal growth by disrupting cell membrane integrity, leading to increased membrane permeability and release of intracellular electrolytes. Antifungal agent 106 can be used in research related to brown rot of stone fruits[1].

IC50 & Target

mTOR

0.8 μM (IC50)

体外研究
(In Vitro)

Antifungal agent 106 (3.125-50 mg/L) 对 M. fructicola 具有抑制活性，可抑制其孢子萌发和菌丝体形成，并通过诱导产生过量的内源性活性氧 (ROS) 在 M. fructicola 中引起细胞氧化损伤、酶失活和细胞膜破坏[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antifungal agent 106 相关抗体:
体内研究
(In Vivo)

Antifungal agent 106 处理 (100 mg/L 和 200 mg/L，喷洒，给药时长 24 小时) 的植物体 (梨) 表现出明显较低的褐腐病发生率和较小的病斑直径，表明 Antifungal agent 106 对石果褐腐病具有抑制活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

434.30

Formula

C20H21BrFN3O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antifungal agent 106 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifungal agent 106Antifungal agent106Antifungal agent-106mTORFungalMammalian target of RapamycinStone fruit brown rotAntifungal activityInhibitorinhibitorinhibit

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