mTOR Inhibitors

mTOR

mTORC1

mTORC2

mTOR Inhibitors, Activators & Modulators

Product Name	mTOR	mTORC1	mTORC2	Purity
Rapamycin		mTOR, IC₅₀: 0.1 nM (in HEK293 cells )		99.94%
MHY1485		mTORC1	mTORC2	99.86%
Everolimus		mTOR, IC₅₀: 5-6 nM		99.85%
Torin 1	mTOR, IC₅₀: 3 nM	mTORC1, IC₅₀: 2-10 nM	mTORC2, IC₅₀: 2-10 nM	99.08%
AZD-8055	mTOR, IC₅₀: 0.8 nM			99.60%
Gedatolisib	mTOR, IC₅₀: 1.6 nM			99.68%
Sapanisertib	mTOR, IC₅₀: 1 nM			99.66%
Salidroside	mTOR			99.79%
Dactolisib	mTOR, IC₅₀: 20.7 nM			99.94%
Temsirolimus		mTOR, IC₅₀: 1.76 μM		99.56%
L-Leucine		mTORC1		99.79%
Torin 2	mTOR, IC₅₀: 2.81 nM mTOR, EC₅₀: 0.25 nM (Cell Assay)			99.65%
3BDO	mTOR			99.93%
PI-103		mTORC1, IC₅₀: 20 nM	mTORC2, IC₅₀: 83 nM	98.93%
RMC-5552		mTORC1		98.10%
Omipalisib		mTORC1, Ki: 0.18 nM	mTORC2, Ki: 0.3 nM	99.93%
JR-AB2-011			mTORC2, IC₅₀: 0.36 μM	99.16%
RapaLink-1	mTOR			99.27%
Camonsertib	mTOR, IC₅₀: 120 nM			99.75%
Dihydromyricetin		mTORC1	mTORC2	98.10%
Torkinib	mTOR, IC₅₀: 8 nM	mTORC1, IC₅₀: 30 nM	mTORC2, IC₅₀: 58 nM	98.37%
hSMG-1 inhibitor 11j	mTOR, IC₅₀: 50 nM			99.82%
Vistusertib	mTOR, IC₅₀: 2.81 nM			98.91%
Aloe emodin			mTORC2	98.32%
KU-0063794		mTORC1, IC₅₀: 10 nM	mTORC2, IC₅₀: 10 nM	99.55%
Samotolisib	mTOR, IC₅₀: 165 nM			99.27%
PF-04691502	mTOR, Ki: 16 nM			99.91%
hSMG-1 inhibitor 11e	mTOR, IC₅₀: 45 nM			99.81%
Dactolisib Tosylate	mTOR, IC₅₀: 20.7 nM			99.87%
Apitolisib	mTOR, Ki: 17 nM			99.29%
CC-115	mTOR, IC₅₀: 21 nM			99.82%
Voxtalisib	mTOR, IC₅₀: 157 nM	mTORC1, IC₅₀: 160 nM	mTORC2, IC₅₀: 910 nM	98.81%
Paxalisib	mTOR, Ki: 70 nM			99.63%
Ridaforolimus		mTOR		99.28%
WYE-132	mTOR, IC₅₀: 0.19 nM			99.90%
BGT226	mTOR			99.51%
GSK1059615	mTOR, IC₅₀: 12 nM			≥99.0%
Onatasertib	mTOR, IC₅₀: 16 nM			99.13%
Bimiralisib	mTOR, IC₅₀: 89 nM			99.80%
OSI-027	mTOR, IC₅₀: 4 nM	mTORC1, IC₅₀: 22 nM	mTORC2, IC₅₀: 65 nM	99.40%
mTOR inhibitor-3	mTOR, Ki: 1.5 nM			99.09%
PKI-402	mTOR, IC₅₀: 3 nM			98.43%
PP121	mTOR, IC₅₀: 10 nM			98.67%
VS-5584	mTOR, IC₅₀: 37 nM			99.14%
BGT226 maleate	mTOR			99.87%
CZ415	mTOR, pIC₅₀: 8.07			98.39%
GNE-317	mTOR			99.14%
PI-103 Hydrochloride		mTORC1, IC₅₀: 20 nM	mTORC2, IC₅₀: 83 nM	98.00%
PQR530	mTOR, Kd: 0.33 nM			99.98%
(+)-Usnic acid		mTORC1	mTORC2	99.63%
CC-115 hydrochloride	mTOR, IC₅₀: 21 nM			98.03%
WYE-354	mTOR, IC₅₀: 5 nM			98.04%
ETP-46464	mTOR, IC₅₀: 0.6 nM			99.55%
WAY-600	mTOR, IC₅₀: 9 nM			99.75%
Rotundic acid	mTOR			99.41%
GDC-0349	mTOR, Ki: 3.8 nM			98.02%
Palomid 529		TORC1	TORC2	99.47%
PQR620		mTORC1	mTORC2	98.01%
HDACs/mTOR Inhibitor 1	mTOR, IC₅₀: 1.2 nM			99.01%
PKI-179	mTOR, IC₅₀: 0.42 nM			≥98.0%
MT 63-78		mTORC1		98.50%
NSC781406	mTOR, IC₅₀: 5.4 nM			99.97%
PF-04979064	mTOR, Ki: 1.42 nM			99.54%
ETP-45658	mTOR, IC₅₀: 152.0 nM			98.97%
Arnicolide D	mTOR			99.20%
Hederacolchiside A1	mTOR			99.69%
GNE-477	mTOR, Ki: 21 nM			98.75%
PI3K/mTOR Inhibitor-2	mTOR, IC₅₀: 4.7 nM			99.10%
PI3K/mTOR Inhibitor-4	mTOR, IC₅₀: 13.85 nM
Zederone	mTOR			99.61%
WYE-687	mTOR, IC₅₀: 7 nM			98.05%
XL388	mTOR, IC₅₀: 9.9 nM			99.74%
GNE-493	mTOR, IC₅₀: 30 nM
MTI-31	mTOR, Ki: 0.2 nM mTOR, IC₅₀: 39 nM (100 μM ATP)			99.98%
AZD3147		mTORC1	mTORC2	99.93%
mTOR inhibitor-8	mTOR
TML-6	mTOR			99.01%
HTH-01-091	mTOR, IC₅₀: 632 nM			98.64%
FT-1518		mTORC1	mTORC2	98.14%
CC214-2		mTORC1	mTORC2	98.41%
PKI-179 hydrochloride	mTOR, IC₅₀: 0.42 nM			99.66%
8-Aminoadenosine	mTOR			99.94%
Coronarin A		mTORC1		≥98.0%
FD274	mTOR, IC₅₀: 2.03 nM
PI3K-IN-18	mTOR, IC₅₀: 49 nM			≥99.0%
Pomiferin	mTOR, IC₅₀: 6.2 μM			98.98%
WYE-687 dihydrochloride	mTOR, IC₅₀: 7 nM			≥98.0%
PI3K-IN-37	mTOR, IC₅₀: 4 nM			≥99.0%
PI3K-IN-22	mTOR, IC₅₀: 0.6 nM			99.50%
PI3Kα/mTOR-IN-1	mTOR, Ki: 10.6 nM			99.30%
GNE-490	mTOR, IC₅₀: 750 nM
HSP90/mTOR-IN-1	mTOR, IC₅₀: 29 nM
ATM Inhibitor-4	mTOR
Antifungal agent 106	mTOR, IC₅₀: 0.8 μM
PI3K/mTOR Inhibitor-3	mTOR
mTOR/HDAC-IN-1	mTOR, IC₅₀: 0.49 nM
PI3K/mTOR Inhibitor-9	mTOR, IC₅₀: 38 nM (phospho-S6 cellular assay) mTOR, IC₅₀: 16 nM (Ser240/244 cellular assay)
PI3K/mTOR Inhibitor-8	mTOR, IC₅₀: 12 nM
ATR-IN-20	mTOR, IC₅₀: 18 nM
PI3K/mTOR Inhibitor-14	mTOR, IC₅₀: 10.1 nM
PI3Kα-IN-5	mTOR, IC₅₀: 3.3 nM
mTOR/HDAC6-IN-1	mTOR, IC₅₀: 133.7 nM
ATM Inhibitor-3	mTOR
PI3K/mTOR Inhibitor-12	mTOR, IC₅₀: 3.12 nM
SN32976	mTOR, IC₅₀: 194 nM
mTOR inhibitor-10	mTOR, IC₅₀: 0.7 nM
mTOR inhibitor-13	mTOR, IC₅₀: 0.29 nM
mTOR inhibitor-16	mTOR, IC₅₀: 1.25 nM
mTOR inhibitor-17	mTOR, IC₅₀: 0.68 nM
PI3K/mTOR Inhibitor-1	mTOR, IC₅₀: 186 nM
mTOR inhibitor-2	mTOR, IC₅₀: 7 nM

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