2. Cell Cycle/DNA Damage PI3K/Akt/mTOR
  3. ATM/ATR PI3K mTOR
  4. ATM Inhibitor-3

ATM Inhibitor -3 (化合物 34) 是一种强效的选择性 ATM 抑制剂，其 IC50 为 0.71 nM。ATM Inhibitor-3 对 PI3K 激酶家族有抑制作用。ATM Inhibitor-3 具有良好的代谢稳定性。

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ATM Inhibitor-3 Chemical Structure

ATM Inhibitor-3 Chemical Structure

CAS No. : 2769140-52-3

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ATM Inhibitor-3 相关抗体

Top Publications Citing Use of Products

查看 ATM/ATR 亚型特异性产品:

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ATM ATR

查看 PI3K 亚型特异性产品:

查看所有亚型
PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

查看 mTOR 亚型特异性产品:

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mTOR mTORC1 mTORC2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ATM Inhibitor-3 (compound 34) is a potent and selective ATM inhibitor, with an IC50 of 0.71 nM. ATM Inhibitor-3 shows inhibition of PI3K kinases family. ATM Inhibitor-3 exhibits favorable metabolic stability[1].

IC50 & Target

ATM

0.71 nM (IC50)

PI3K

 

mTOR

 

分子量

480.53

Formula

C25H29FN6O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ATM Inhibitor-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATM Inhibitor-32769140-52-3ATM Inhibitor3ATM Inhibitor 3ATM/ATRPI3KmTORAtaxia telangiectasia mutatedATM and RAD3 relatedPhosphoinositide 3-kinaseMammalian target of RapamycinA549 NSCLC cellsDNA damage responseDDRAtaxia-Telangiectasia-mutated kinaseInhibitorinhibitorinhibit

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