2. PI3K/Akt/mTOR
  3. mTOR
  4. mTOR inhibitor-2

mTOR inhibitor-2 是有效，选择性，可口服的 mTOR 抑制剂，IC50为7 nM。mTOR Inhibitor 1抑制mTORC1 (pS6 and p4E-BP1) 和mTORC2 (pAKT (S473)) 底物的细胞磷酸化。

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mTOR inhibitor-2 Chemical Structure

mTOR inhibitor-2 Chemical Structure

CAS No. : 2219323-96-1

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mTOR inhibitor-2 相关抗体

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mTOR mTORC1 mTORC2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].

IC50 & Target

mTOR

7 nM (IC50)

分子量

411.46

Formula

C23H21N7O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

mTOR inhibitor-2 相关分类

  • 摩尔计算器

  • 稀释计算器

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

mTOR inhibitor-22219323-96-1mTOR inhibitor2mTOR inhibitor 2mTORMammalian target of RapamycinInhibitorinhibitorinhibit

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