2. Anti-infection
  3. Antibiotic
  4. Aranciamycin

Aranciamycin  (Synonyms: 阿雷西霉素)

目录号: HY-123886
产品使用指南

摩尔计算器

Aranciamycin (Compound 1) 是一类蒽环类抗生素，具有胶原酶抑制活性 (IC503.7*10-7M)。Aranciamycin 能够用于抑制肿瘤细胞DNA合成的研究。

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Aranciamycin Chemical Structure

Aranciamycin Chemical Structure

CAS No. : 72389-06-1

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Aranciamycin 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Aranciamycin (Compound 1) is an anthracycline antibiotic with collagenase inhibitory activity (IC503.7*10-7M). Aranciamycin can be used to inhibit DNA synthesis in tumor cells [1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HeLa IC50
2.7 μM
Compound: 3
Cytotoxicity against human HeLa cells after 48 hrs by WST8 assay
Cytotoxicity against human HeLa cells after 48 hrs by WST8 assay
[PMID: 20192240]
HepG2 IC50
18 μM
Compound: 4
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 25789410]
HL-60 IC50
4.1 μM
Compound: 3
Cytotoxicity against human HL60 cells after 48 hrs by WST8 assay
Cytotoxicity against human HL60 cells after 48 hrs by WST8 assay
[PMID: 20192240]
KB 3-1 IC50
> 30 μM
Compound: 4
Cytotoxicity against human KB-3-1 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human KB-3-1 cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 25789410]
NCI-H460 IC50
> 30 μM
Compound: 4
Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 25789410]
SW-620 IC50
> 30 μM
Compound: 4
Cytotoxicity against human SW620 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human SW620 cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 25789410]
分子量

544.50

Formula

C27H28O12
CAS 号
中文名称

阿雷西霉素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Aranciamycin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aranciamycin72389-06-1阿雷西霉素Antibioticcollagenase anthracycline antibiotictumor cellsInhibitorinhibitorinhibit

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