2. GPCR/G Protein Apoptosis
  3. Vasopressin Receptor Apoptosis
  4. Argipressin acetate

Argipressin acetate  (Synonyms: Arg8-vasopressin acetate; AVP acetate)

目录号: HY-W539944
产品使用指南

摩尔计算器

Argipressin (Arg8-vasopressin) (acetate) 可与血管精氨酸加压素受体 V1、V2 和 V3结合，其在 A7r5 大鼠主动脉平滑肌细胞中对 V1 的 Kd 值为 1.31 nM。

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Custom Peptide Synthesis

Argipressin acetate Chemical Structure

Argipressin acetate Chemical Structure

CAS No. : 129979-57-3

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Argipressin acetate 的其他形式现货产品:

Customer Review

Other Forms of Argipressin acetate:

Argipressin acetate 相关抗体

Top Publications Citing Use of Products

查看 Vasopressin Receptor 亚型特异性产品:

查看所有亚型
V1a Receptor  V1b Receptor  V2 Receptor 

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1[1][2][3][4].

体外研究
(In Vitro)

Argipressin (Arg8-vasopressin) (acetate) 在啮齿动物和人类 β 细胞中诱导增殖并阻止细胞因子诱导的细胞凋亡[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Argipressin acetate 相关抗体:

Cell Proliferation Assay[1]

Cell Line: clonal BRIN BD11 and 1.1B4 cells
Concentration: 10-6 M
Incubation Time: 2 h
Result: Increased proliferation of rodent and human beta-cells.

Apoptosis Analysis[1]

Cell Line: clonal BRIN BD11 and 1.1B4 cells
Concentration: 10-6 M
Incubation Time: 2 h
Result: Protected against cytokine-induced beta-cell apoptosis.
体内研究
(In Vivo)

Argipressin (diacetate) (AVP (diacetate)) (25 nmol/kg bw; 腹腔内注射; 一次) 显著降低小鼠的总体 AUC 葡萄糖值，但不增加小鼠的胰岛素水平[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: NIH Swiss mice (adult; male; 12-14weeks)[1]
Dosage: 25 nmol/kg bw
Administration: AVP (25 nmol/kg bw; intraperitoneal injection; once)
Result: Reduced (P<0.001) overall AUC glucose values，but not increased insulin levels in mice.
Clinical Trial
分子量

1144.28

Formula

C₄₈H₆₉N₁₅O₁₄S₂
CAS 号
Sequence Shortening

CYFQNCPRG-NH2 (Disulfide bridge: Cys1-Cys6)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Argipressin acetate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Argipressin129979-57-3Arg8-vasopressinAVPVasopressin ReceptorApoptosisArginine vasopressinADHfluid balanceosmolalityInhibitorinhibitorinhibit

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