1. Immunology/Inflammation
  2. Interleukin Related
  3. Astegolimab

Astegolimab  (Synonyms: 艾特利单抗; MSTT 1041A; RG 6149)

目录号: HY-P99444 纯度: 98.96%
COA

Astegolimab (MSTT 1041A; RG 6149) 是一种人 IgG2 单克隆抗体,可通过靶向 IL-33 受体 ST2 来阻断 IL-33 信号传导。Astegolimab 具有用于慢性阻塞性肺疾病 (COPD) 研究的潜力。

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CAS No. : 2173054-79-8

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规格 价格 是否有货 数量
1 mg ¥3000
In-stock
5 mg ¥7900
In-stock
10 mg   询价  
50 mg   询价  

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2, the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research[1].

同型

Human IgG2 kappa

推荐同型对照抗体
种属

Human

IC50 & Target[1]

ST2

 

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

艾特利单抗

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG2 kappa
Biological Activity
  • Immobilized ST2/IL1RL1 Protein, Human can bind Astegolimab. The EC50 for this effect is 28.29 ng/mL.
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Astegolimab
目录号:
HY-P99444
需求量: