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  2. 酚类 海洋天然产物
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  4. Avarol

Avarol  (Synonyms: (+)-Avarol)

目录号: HY-121794
产品使用指南

Avarol 是一种倍半萜对苯二酚,可从 Dysidea avara sponge 中分离得到。Avarol 具有用于艾氏癌 (EC) 和宫颈癌 (CC-5) 研究的潜力。

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Avarol Chemical Structure

Avarol Chemical Structure

CAS No. : 55303-98-5

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规格 价格 是否有货 数量
1 mg ¥3600
3 - 4 周
5 mg   询价  
10 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Avarol is a sesquiterpene hydroquinone that can be isolated from Dysidea avara sponge. Avarol has the potential for the research of ehrlich carcinoma (EC) and cervical cancer (CC-5)[1].

体外研究
(In Vitro)

Avarol (12.5, 25, 50, 100, 200 µg/mL; 72 h) 对 HeLa、LS174、A549、MRC-5 细胞表现出细胞毒性,IC50 值分别为 10.22、34.06、35.27、29.14 µg/mL[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: HeLa, LS174, A549, MRC-5 cells
Concentration: 12.5, 25, 50, 100, 200 µg/mL
Incubation Time: 72 h
Result: Exhibited the cytotoxic for HeLa, LS174, A549, MRC-5 cells with IC50s of 10.22, 34.06, 35.27, 29.14 µg/mL, respectively.
体内研究
(In Vivo)

Avarol (50 mg/kg; i.p.; daily for 14 days) 在小鼠中表现出抗肿瘤活性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: female F1 (CBA × C57BL/6j) mice (Ehrlich carcinoma)[1]
Dosage: 50 mg/kg
Administration: I.p.; daily for 14 days
Result: Inhibited tumor growth with a stable inhibition (25-35%) of EC growth.
分子量

314.46

Formula

C21H30O2

CAS 号
结构分类
初始来源

Dysidea avara

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Avarol
目录号:
HY-121794
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