2. GPCR/G Protein
  3. GHSR
  4. AZ-GHS-22

AZ-GHS-22 是一种有效的非 CNS 渗透性 GHS-R1a 反向激动剂 (IC50=0.77 nM)。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

我们将采用定制合成服务的方式为您快速提供所需产品和技术服务

AZ-GHS-22 Chemical Structure

AZ-GHS-22 Chemical Structure

CAS No. : 1143020-91-0

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥1530
3 - 4 周
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

AZ-GHS-22 相关抗体

Top Publications Citing Use of Products

查看 GHSR 亚型特异性产品:

查看所有亚型
GHSR1a

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AZ-GHS-22 is a potent, non-CNS penetrant GHS-R1a inverse agonist (IC50=0.77 nM)[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 IC50
0.77 nM
Compound: 22
Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
[PMID: 24967667]
HEK293 IC50
1.1 nM
Compound: 22
Displacement of [125I]human ghrelin from mouse GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
Displacement of [125I]human ghrelin from mouse GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
[PMID: 24967667]
HEK293 IC50
3.4 nM
Compound: 22
Displacement of [125I]human ghrelin from rat GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
Displacement of [125I]human ghrelin from rat GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
[PMID: 24967667]
分子量

621.17

Formula

C27H33ClN6O5S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AZ-GHS-22 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZ-GHS-221143020-91-0GHSRGrowth hormone secretagogue receptorGhrelin receptornon-CNS penetrant inverse agonistGhrelinfood intakeantiobesityInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
AZ-GHS-22
目录号：
HY-137061
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z