1. Anti-infection
  2. Antibiotic Bacterial
  3. Balhimycin

Balhimycin 是一种糖肽类抗生素,发现于 Amycolatopsis sp. 的发酵液,Balhimycin 具有对葡萄球菌和厌氧菌的抗菌活性。

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Custom Peptide Synthesis

Balhimycin Chemical Structure

Balhimycin Chemical Structure

CAS No. : 140932-79-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Balhimycin is a glycopeptide antibiotic, found from the fermentation broth of a Amycolatopsis sp. Balhimycin shows anti-bacterial activity against staphylococci and anaerobes[1].

IC50 & Target

Glycopeptide

 

体外研究
(In Vitro)

Balhimycin (0.39-12.5 μg/mL; 18 h) shows bactericidal activity against S. aureus, Streptococcus epidermidis, and streptococcal strains[1].
Balhimycin (0.39-12.5 μg/mL; 18 h) shows good bactericidal activity against different Staphylococcal strains[1].
Balhimycin (1-15 μg/mL; 30 min) leads to cell membrane scrambling of platelets, and shows stimulation of platelet apoptosis[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Staphylococcus aureus 209P, S. aureus 3066, S. aureus 20424, S. epidermidis 178, S. epidermidis 825, S. epidermidis 823, S. haemolyticus 712, S. haemolyticus 809, Streptococcus ATCC 29212, S. faecalis D 21777, S. faecalis D Endococcen, S. faecium D-59, S. faecium D-65
Concentration: 0.39-12.5 μg/mL
Incubation Time: 18 hours
Result: Showed MIC values ranging from 0.39 μg/mL to 12.5 μg/mL against S. aureus, Streptococcus epidermidis, and streptococcal strains.

Cell Viability Assay[1]

Cell Line: Staphylococcus aureus 3066, S. aureus 20424, S. epidermidis 825, S. haemolyticus 712, Streptococcus faecalis ATCC29212, S. faecalis D 21777, S. faecalis D-59
Concentration: 0.39-1.56 μg/mL
Incubation Time: 18 hours
Result: Showed MIC values ranging from 0.39 μg/mL to 1.56 μg/mL against staphylococcal strains.
分子量

1447.24

Formula

C66H73Cl2N9O24

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Balhimycin
目录号:
HY-148209
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