2. Metabolic Enzyme/Protease Others
  3. PI5P4K Others
  4. BAY-091

BAY-091 是一种新型高效、高选择性的 PIP4K2A 激酶抑制剂。

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BAY-091 Chemical Structure

BAY-091 Chemical Structure

CAS No. : 2922280-34-8

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥945
In-stock
5 mg ￥2338
In-stock
10 mg ￥3438
In-stock
25 mg ￥5481
In-stock
50 mg 现货 询价
100 mg 现货 询价
500 mg 现货 询价
1 g   询价  
5 g   询价  

* Please select Quantity before adding items.

Customer Review

BAY-091 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BAY-091 is a novel potent and highly selective inhibitor of the kinase PIP4K2A.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
EBC-1 IC50
30 μM
Compound: 60; BAY-091
Antiproliferative activity against human EBC-1 cells harboring p53 mutation assessed as reduction in cell viability incubated for 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human EBC-1 cells harboring p53 mutation assessed as reduction in cell viability incubated for 72 hrs by CellTiter-Glo assay
[PMID: 34699202]
NCI-H460 IC50
> 30 μM
Compound: 60; BAY-091
Antiproliferative activity against human NCI-H460 cells harboring wild type p53 assessed as reduction in cell viability incubated for 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human NCI-H460 cells harboring wild type p53 assessed as reduction in cell viability incubated for 72 hrs by CellTiter-Glo assay
[PMID: 34699202]
THP-1 IC50
> 30 μM
Compound: 60; BAY-091
Antiproliferative activity against human THP-1 cells harboring p53 mutation assessed as reduction in cell viability incubated for 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human THP-1 cells harboring p53 mutation assessed as reduction in cell viability incubated for 72 hrs by CellTiter-Glo assay
[PMID: 34699202]
分子量

440.47

Formula

C26H21FN4O2
CAS 号
性状

固体

颜色

Light yellow to light brown

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 125 mg/mL (283.79 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.2703 mL 11.3515 mL 22.7030 mL
5 mM 0.4541 mL 2.2703 mL 4.5406 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

BAY-091 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2703 mL 11.3515 mL 22.7030 mL 56.7576 mL
5 mM 0.4541 mL 2.2703 mL 4.5406 mL 11.3515 mL
10 mM 0.2270 mL 1.1352 mL 2.2703 mL 5.6758 mL
15 mM 0.1514 mL 0.7568 mL 1.5135 mL 3.7838 mL
20 mM 0.1135 mL 0.5676 mL 1.1352 mL 2.8379 mL
25 mM 0.0908 mL 0.4541 mL 0.9081 mL 2.2703 mL
30 mM 0.0757 mL 0.3784 mL 0.7568 mL 1.8919 mL
40 mM 0.0568 mL 0.2838 mL 0.5676 mL 1.4189 mL
50 mM 0.0454 mL 0.2270 mL 0.4541 mL 1.1352 mL
60 mM 0.0378 mL 0.1892 mL 0.3784 mL 0.9460 mL
80 mM 0.0284 mL 0.1419 mL 0.2838 mL 0.7095 mL
100 mM 0.0227 mL 0.1135 mL 0.2270 mL 0.5676 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BAY-0912922280-34-8BAY091BAY 091PI5P4KOthersPIP4KInhibitorinhibitorinhibit

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产品名称：
BAY-091
目录号：
HY-139868
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