2. GPCR/G Protein
  3. Leukotriene Receptor
  4. BAY-u 9773

BAY-u 9773 是一种非选择性的 CysLT 受体 (半胱氨酸白三烯受体)拮抗剂，对于 CysLT1 和 CysLT2 的 IC50 值大约相等，用于抑制白三烯反应。

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BAY-u 9773 Chemical Structure

BAY-u 9773 Chemical Structure

CAS No. : 154978-38-8

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规格 价格 是否有货 数量
25 μg ￥1339
3 - 4 周
50 μg 询价

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BAY-u 9773 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

查看 Leukotriene Receptor 亚型特异性产品:

查看所有亚型
LTB4 LTC4/CysLT2 LTD4/CysLT1 LTE4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BAY-u 9773 is a non-selective antagonist of the CysLT receptors (cysteinyl leukotrienes receptors) with about the same IC50 for CysLT1 and CysLT2. BAY-u9773 is used for the inhibition of LT responses[1].

IC50 & Target

LTD4

 

LTC4

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CHO IC50
0.44 μM
Compound: BAY-u9773
Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay
Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay
[PMID: 25408836]
HEK293 IC50
0.3 μM
Compound: BAY-u9773
Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay
Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay
[PMID: 25408836]
分子量

472.64

Formula

C27H36O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BAY-u 9773 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BAY-u 9773154978-38-8Leukotriene ReceptorInhibitorinhibitorinhibit

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产品名称：
BAY-u 9773
目录号：
HY-107609
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